Bt03219290_m1 Best Coverage

• Gene Symbol: PARK7
• Gene Name: Parkinsonism associated deglycase
• Gene Aliases: DJ-1, DJ1
• Chromosome Location: Chr.16: 45400216 - 45417097 on Build ARS-UCD1.2
• Species: Bovine
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: PARK7
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001015572.1	NP_001015572.1	6 - 7	519		75
GenBank mRNA	BC102707.1	-	6 - 7	540		75
	BT021074.1	-	6 - 7	519		75

More Information

• Set Membership: Amplicon length between 71 and 85, 3' Most, Mammalian Gene Collection, Recommended Assay, Bos taurus, Probe spans exons

Gene Ontology Categories:

Process(es)

positive regulation of acute inflammatory response to antigenic stimulus
DNA repair
negative regulation of protein kinase activity
proteolysis
protein deglycosylation
autophagy
inflammatory response
mitochondrion organization
single fertilization
adult locomotory behavior
methylglyoxal metabolic process
detoxification of copper ion
negative regulation of gene expression
histone modification
enzyme active site formation via L-cysteine sulfinic acid
insulin secretion
positive regulation of protein complex assembly
negative regulation of protein binding
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of interleukin-8 production
positive regulation of peptidyl-serine phosphorylation
regulation of histone ubiquitination
negative regulation of protein sumoylation
positive regulation of NAD(P)H oxidase activity
cellular response to oxidative stress
regulation of histone acetylation
cellular response to glyoxal
peptidyl-cysteine deglycation
peptidyl-arginine deglycation
peptidyl-lysine deglycation
protein deglycation, methylglyoxal removal
glutathione deglycation
glucose homeostasis
hydrogen peroxide metabolic process
regulation of neuron apoptotic process
positive regulation of transcription from RNA polymerase II promoter
negative regulation of protein export from nucleus
regulation of inflammatory response
detoxification of mercury ion
protein stabilization
negative regulation of ubiquitin-protein transferase activity
dopamine uptake involved in synaptic transmission
regulation of mitochondrial membrane potential
membrane depolarization
membrane hyperpolarization
negative regulation of cell death
regulation of androgen receptor signaling pathway
methylglyoxal catabolic process to lactate
cellular response to hydrogen peroxide
cellular oxidant detoxification
guanine deglycation
guanine deglycation, methylglyoxal removal
guanine deglycation, glyoxal removal
cellular detoxification of aldehyde
cellular detoxification of methylglyoxal
positive regulation of protein localization to nucleus
positive regulation of superoxide dismutase activity
negative regulation of protein acetylation
positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
positive regulation of mitochondrial electron transport, NADH to ubiquinone
negative regulation of protein K48-linked deubiquitination
negative regulation of TRAIL-activated apoptotic signaling pathway
positive regulation of pyrroline-5-carboxylate reductase activity
positive regulation of tyrosine 3-monooxygenase activity
positive regulation of dopamine biosynthetic process
glyoxal catabolic process
positive regulation of L-dopa biosynthetic process
positive regulation of L-dopa decarboxylase activity
negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway
negative regulation of reactive oxygen species biosynthetic process
positive regulation of reactive oxygen species biosynthetic process
negative regulation of nitrosative stress-induced intrinsic apoptotic signaling pathway
negative regulation of ubiquitin-specific protease activity
positive regulation of oxidative phosphorylation uncoupler activity
positive regulation of transcription regulatory region DNA binding
positive regulation of androgen receptor activity
negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Function(s)

transcription coactivator activity
mRNA binding
copper ion binding
peptidase activity
superoxide dismutase copper chaperone activity
kinase binding
cytokine binding
tyrosine 3-monooxygenase activator activity
L-dopa decarboxylase activator activity
protein deglycase activity
protein homodimerization activity
small protein activating enzyme binding
ubiquitin-like protein conjugating enzyme binding
macromolecular complex binding
mercury ion binding
androgen receptor binding
peroxiredoxin activity
repressing transcription factor binding
scaffold protein binding
cupric ion binding
cuprous ion binding
ubiquitin-specific protease binding
glyoxalase (glycolic acid-forming) activity