Cf02716206_u1 Best Coverage

• Gene Symbol: PDGFB
• Gene Name: platelet derived growth factor subunit B
• Gene Aliases: PDGF-B
• Chromosome Location: Chr.10: 25798877 - 25819422 on Build CanFam3.1
• Species: Dog
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: PDGFB
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001003383.1	NP_001003383.1	3	179		149
	XM_005625680.3	XP_005625737.1	3	240		149
	XM_005625682.3	XP_005625739.1	3	240		149
	XM_005625683.3	XP_005625740.1	3	240		149
	XM_022423987.1	XP_022279695.1	3	272		149
GenBank mRNA	AY553983.1	-	3	179		149

More Information

Additional Information:

This assay maps with 100% identity to the human homologue, and the human gene symbol was added in the Alias field to assist with searches.

• Set Membership: Amplicon length greater than or equal to 101, Recommended Assay, Canis familiaris, Amplicon spans exons and probe does not span exons

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

embryonic placenta development
positive regulation of endothelial cell proliferation
monocyte chemotaxis
positive regulation of glomerular filtration
protein phosphorylation
heart development
positive regulation of cell proliferation
response to wounding
negative regulation of phosphatidylinositol biosynthetic process
negative regulation of platelet activation
positive regulation of phosphatidylinositol 3-kinase signaling
positive regulation of smooth muscle cell migration
peptidyl-serine phosphorylation
peptidyl-tyrosine phosphorylation
hemopoiesis
positive regulation of protein autophosphorylation
activation of protein kinase activity
activation of protein kinase B activity
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
paracrine signaling
positive regulation of MAP kinase activity
positive regulation of MAPK cascade
positive regulation of blood vessel endothelial cell migration
positive regulation of phosphatidylinositol 3-kinase activity
positive regulation of cyclin-dependent protein serine/threonine kinase activity
positive regulation of mitotic nuclear division
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
platelet-derived growth factor receptor signaling pathway
positive regulation of fibroblast proliferation
positive regulation of smooth muscle cell proliferation
positive regulation of chemotaxis
positive regulation of cell division
cell chemotaxis
positive regulation of protein tyrosine kinase activity
positive regulation of ERK1 and ERK2 cascade
cellular response to mycophenolic acid
positive regulation of glomerular mesangial cell proliferation
metanephric glomerular mesangial cell development
reactive oxygen species metabolic process
positive regulation of calcium ion import
positive regulation of hyaluronan biosynthetic process
positive regulation of vascular smooth muscle cell proliferation
positive regulation of reactive oxygen species metabolic process
positive regulation of DNA biosynthetic process
positive regulation of metanephric mesenchymal cell migration

Function(s)

platelet-derived growth factor receptor binding
growth factor activity
superoxide-generating NADPH oxidase activator activity
protein homodimerization activity