Assay Details
Gene Symbol: PTGS2 | ||||||
---|---|---|---|---|---|---|
Interrogated Sequence | Translated Protein | Exon Boundary | Assay Location | IMAGE Clone ID | Amplicon Length | |
RefSeq | NM_000963.3 | NP_000954.1 | 5 - 6 | 777 | 75 | |
GenBank mRNA | AJ634912.1 | - | 5 - 6 | 530 | 75 | |
AK292167.1 | - | 5 - 6 | 765 | 75 | ||
AY151286.1 | - | 5 - 6 | 737 | 75 | ||
AY462100.1 | - | 5 - 6 | 640 | 75 | ||
BC013734.1 | - | 5 - 6 | 760 | 3880850 | 75 | |
L15326.1 | - | 5 - 6 | 732 | 75 | ||
M90100.1 | - | 5 - 6 | 737 | 75 |

More Information
Updated Mapping Information

This assay targets the same location as HTA transcript cluster(s) TC01003638.hg.1
Set Membership: |
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Matching Ambion siRNAs:
Panther Classification:
Gene Ontology Categories:
MicroArray Probes:

Citations (41)
NSAID-induced antral ulcers are associated with distinct changes in mucosal gene expression.
- Authors
- Desai JC, Goo T, Fukata M, Sanyal S, Dikman A, Miller K, Cohen L, Brooks A, Wang Q, Abreu MT, Aisenberg J
- Journal
- Aliment Pharmacol Ther - Page No 71 (Wed Jul 01 00:00:00 EDT 2009)
- Volume (Year)
- 30 (2009)
- Product Usage
- -
Expression of eicosanoid biosynthetic and catabolic enzymes in peritoneal endometriosis.
- Authors
- Lousse JC, Defrere S, Colette S, Van Langendonckt A, Donnez J
- Journal
- Hum Reprod - Page No 734 (Mon Mar 01 00:00:00 EST 2010)
- Volume (Year)
- 25 (2010)
- Product Usage
- -
Supercritical fluid extraction of oregano (Origanum vulgare) essentials oils: anti-inflammatory properties based on cytokine response on THP-1 macrophages.
- Authors
- Ocana-Fuentes A, Arranz-Gutierrez E, Senorans FJ, Reglero G
- Journal
- Food Chem Toxicol - Page No 1568 (Tue Jun 01 00:00:00 EDT 2010)
- Volume (Year)
- 48 (2010)
- Product Usage
- -
Key regulatory molecules of cartilage destruction in rheumatoid arthritis: an in vitro study.
- Authors
- Andreas K, Lubke C, Haupl T, Dehne T, Morawietz L, Ringe J, Kaps C, Sittinger M
- Journal
- Arthritis Res Ther - Page No R9 (Tue Jan 01 00:00:00 EST 2008)
- Volume (Year)
- 10 (2008)
- Product Usage
- -
Interleukin-17A inhibits adipocyte differentiation in human mesenchymal stem cells and regulates pro-inflammatory responses in adipocytes.
- Authors
- Shin JH, Shin DW, Noh M
- Journal
- Biochem Pharmacol - Page No 1835 (Mon Jun 15 00:00:00 EDT 2009)
- Volume (Year)
- 77 (2009)
- Product Usage
- -
Onconase responsive genes in human mesothelioma cells: implications for an RNA damaging therapeutic agent.
- Authors
- Altomare DA, Rybak SM, Pei J, Maizel JV, Cheung M, Testa JR, Shogen K
- Journal
- Bmc Cancer - Page No 34 (Fri Jan 01 00:00:00 EST 2010)
- Volume (Year)
- 10 (2010)
- Product Usage
- -
Dietary lipid hydroperoxides induce expression of vascular endothelial growth factor (VEGF) in human colorectal tumor cells.
- Authors
- Jurek D, Udilova N, Jozkowicz A, Nohl H, Marian B, Schulte-Hermann R
- Journal
- Faseb J - Page No 97 (Sat Jan 01 00:00:00 EST 2005)
- Volume (Year)
- 19 (2005)
- Product Usage
- -
Region-specific gene expression profiling: novel evidence for biological heterogeneity of the human amnion.
- Authors
- Han YM, Romero R, Kim JS, Tarca AL, Kim SK, Draghici S, Kusanovic JP, Gotsch F, Mittal P, Hassan SS, Kim CJ
- Journal
- Biol Reprod - Page No 954 (Sat Nov 01 00:00:00 EDT 2008)
- Volume (Year)
- 79 (2008)
- Product Usage
- -
Effects of selective PGE2 receptor antagonists in esophageal adenocarcinoma cells derived from Barrett's esophagus.
- Authors
- Piazuelo E, Jimenez P, Strunk M, Santander S, Garcia A, Esteva F, Lanas A
- Journal
- Prostaglandins Other Lipid Mediat - Page No 150 (Fri Dec 01 00:00:00 EST 2006)
- Volume (Year)
- 81 (2006)
- Product Usage
- -
N(epsilon)-carboxymethyllysine-modified proteins are unable to bind to RAGE and activate an inflammatory response.
- Authors
- Buetler TM, Leclerc E, Baumeyer A, Latado H, Newell J, Adolfsson O, Parisod V, Richoz J, Maurer S, Foata F, Piguet D, Junod S, Heizmann CW, Delatour T
- Journal
- Mol Nutr Food Res - Page No 370 (Sat Mar 01 00:00:00 EST 2008)
- Volume (Year)
- 52 (2008)
- Product Usage
- -
Gene expression profiling of human mesenchymal stem cells chemotactically induced with CXCL12.
- Authors
- Stich S, Haag M, Haupl T, Sezer O, Notter M, Kaps C, Sittinger M, Ringe J
- Journal
- Cell Tissue Res - Page No 225 (Fri May 01 00:00:00 EDT 2009)
- Volume (Year)
- 336 (2009)
- Product Usage
- -
Peroxisome-proliferator-activated receptors gamma and beta/delta mediate vascular endothelial growth factor production in colorectal tumor cells.
- Authors
- Rohrl C, Kaindl U, Koneczny I, Hudec X, Baron DM, Konig JS, Marian B
- Journal
- J Cancer Res Clin Oncol - Page No (Thu Mar 11 00:00:00 EST 2010)
- Volume (Year)
- (2010)
- Product Usage
- -
Remodeling phenotype of human subcutaneous adipose tissue macrophages.
- Authors
- Bourlier V, Zakaroff-Girard A, Miranville A, De Barros S, Maumus M, Sengenes C, Galitzky J, Lafontan M, Karpe F, Frayn KN, Bouloumie A
- Journal
- Circulation - Page No 806 (Tue Feb 12 00:00:00 EST 2008)
- Volume (Year)
- 117 (2008)
- Product Usage
- -
In vitro and in vivo cytotoxic effects of PRIMA-1 on hepatocellular carcinoma cells expressing mutant p53ser249.
- Authors
- Shi H, Lambert JM, Hautefeuille A, Bykov VJ, Wiman KG, Hainaut P, de Fromentel CC
- Journal
- Carcinogenesis - Page No 1428 (Tue Jul 01 00:00:00 EDT 2008)
- Volume (Year)
- 29 (2008)
- Product Usage
- -
Glutamate signaling in chondrocytes and the potential involvement of NMDA receptors in cell proliferation and inflammatory gene expression.
- Authors
- Piepoli T, Mennuni L, Zerbi S, Lanza M, Rovati LC, Caselli G
- Journal
- Osteoarthritis Cartilage - Page No 1076 (Sat Aug 01 00:00:00 EDT 2009)
- Volume (Year)
- 17 (2009)
- Product Usage
- -
cis-Urocanic acid initiates gene transcription in primary human keratinocytes.
- Authors
- Kaneko K, Smetana-Just U, Matsui M, Young AR, John S, Norval M, Walker SL
- Journal
- J Immunol - Page No 217 (Tue Jul 01 00:00:00 EDT 2008)
- Volume (Year)
- 181 (2008)
- Product Usage
- -
Combination effects of salvianolic acid B with low-dose celecoxib on inhibition of head and neck squamous cell carcinoma growth in vitro and in vivo.
- Authors
- Zhao Y, Hao Y, Ji H, Fang Y, Guo Y, Sha W, Zhou Y, Pang X, Southerland WM, Califano JA, Gu X
- Journal
- Cancer Prev Res (Phila) - Page No 787 (Tue Jun 01 00:00:00 EDT 2010)
- Volume (Year)
- 3 (2010)
- Product Usage
- -
Signal transduction for proteinase-activated receptor-2-triggered prostaglandin E2 formation in human lung epithelial cells.
- Authors
- Kawao N, Nagataki M, Nagasawa K, Kubo S, Cushing K, Wada T, Sekiguchi F, Ichida S, Hollenberg MD, MacNaughton WK, Nishikawa H, Kawabata A
- Journal
- J Pharmacol Exp Ther - Page No 576 (Tue Nov 01 00:00:00 EST 2005)
- Volume (Year)
- 315 (2005)
- Product Usage
- -
Human cumulus granulosa cell gene expression: a predictor of fertilization and embryo selection in women undergoing IVF.
- Authors
- McKenzie LJ, Pangas SA, Carson SA, Kovanci E, Cisneros P, Buster JE, Amato P, Matzuk MM
- Journal
- Hum Reprod - Page No 2869 (Wed Dec 01 00:00:00 EST 2004)
- Volume (Year)
- 19 (2004)
- Product Usage
- -
Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration.
- Authors
- Andreas K, Haupl T, Lubke C, Ringe J, Morawietz L, Wachtel A, Sittinger M, Kaps C
- Journal
- Arthritis Res Ther - Page No R15 (Thu Jan 01 00:00:00 EST 2009)
- Volume (Year)
- 11 (2009)
- Product Usage
- -
Long term NSAID treatment inhibits COX-2 synthesis in the knee synovial membrane of patients with osteoarthritis: differential proinflammatory cytokine profile between celecoxib and aceclofenac.
- Authors
- Alvarez-Soria MA, Largo R, Santillana J, Sanchez-Pernaute O, Calvo E, Hernandez M, Egido J, Herrero-Beaumont G
- Journal
- Ann Rheum Dis - Page No 998 (Tue Aug 01 00:00:00 EDT 2006)
- Volume (Year)
- 65 (2006)
- Product Usage
- -
MAPKAP kinase 2 blocks tristetraprolin-directed mRNA decay by inhibiting CAF1 deadenylase recruitment.
- Authors
- Marchese FP, Aubareda A, Tudor C, Saklatvala J, Clark AR, Dean JL
- Journal
- J Biol Chem - Page No 27590 (Fri Sep 03 00:00:00 EDT 2010)
- Volume (Year)
- 285 (2010)
- Product Usage
- -
Effect of altering dietary omega-6/omega-3 fatty acid ratios on prostate cancer membrane composition, cyclooxygenase-2, and prostaglandin E2.
- Authors
- Kobayashi N, Barnard RJ, Henning SM, Elashoff D, Reddy ST, Cohen P, Leung P, Hong-Gonzalez J, Freedland SJ, Said J, Gui D, Seeram NP, Popoviciu LM, Bagga D, Heber D, Glaspy JA, Aronson WJ
- Journal
- Clin Cancer Res - Page No 4662 (Tue Aug 01 00:00:00 EDT 2006)
- Volume (Year)
- 12 (2006)
- Product Usage
- -
Hypoxia activates the cyclooxygenase-2-prostaglandin E synthase axis.
- Authors
- Lee JJ, Natsuizaka M, Ohashi S, Wong GS, Takaoka M, Michaylira CZ, Budo D, Tobias JW, Kanai M, Shirakawa Y, Naomoto Y, Klein-Szanto AJ, Haase VH, Nakagawa H
- Journal
- Carcinogenesis - Page No 427 (Mon Mar 01 00:00:00 EST 2010)
- Volume (Year)
- 31 (2010)
- Product Usage
- -
Liver X receptor is a therapeutic target for photoaging and chronological skin aging.
- Authors
- Chang KC, Shen Q, Oh IG, Jelinsky SA, Jenkins SF, Wang W, Wang Y, LaCava M, Yudt MR, Thompson CC, Freedman LP, Chung JH, Nagpal S
- Journal
- Mol Endocrinol - Page No 2407 (Sat Nov 01 00:00:00 EDT 2008)
- Volume (Year)
- 22 (2008)
- Product Usage
- -
Differential effects of NF-{kappa}B and p38 MAPK inhibitors and combinations thereof on TNF-{alpha}- and IL-1{beta}-induced proinflammatory status of endothelial cells in vitro.
- Authors
- Kuldo JM, Westra J, Asgeirsdottir SA, Kok RJ, Oosterhuis K, Rots MG, Schouten JP, Limburg PC, Molema G
- Journal
- Am J Physiol Cell Physiol - Page No C1229 (Tue Nov 01 00:00:00 EST 2005)
- Volume (Year)
- 289 (2005)
- Product Usage
- -
NF-kappaB-dependent anti-inflammatory activity of urolithins, gut microbiota ellagic acid-derived metabolites, in human colonic fibroblasts.
- Authors
- Gonzalez-Sarrias A, Larrosa M, Tomas-Barberan FA, Dolara P, Espin JC
- Journal
- Br J Nutr - Page No 503 (Sun Aug 01 00:00:00 EDT 2010)
- Volume (Year)
- 104 (2010)
- Product Usage
- -
Homeobox gene CDX2 inhibits human pancreatic cancer cell proliferation by down-regulating cyclin D1 transcriptional activity.
- Authors
- Takahashi K, Hirano F, Matsumoto K, Aso K, Haneda M
- Journal
- Pancreas - Page No 49 (Thu Jan 01 00:00:00 EST 2009)
- Volume (Year)
- 38 (2009)
- Product Usage
- -
Cytokine-dependent balance of mitogenic effects in primary human lung fibroblasts related to cyclic AMP signaling and phosphodiesterase 4 inhibition.
- Authors
- Selige J, Tenor H, Hatzelmann A, Dunkern T
- Journal
- J Cell Physiol - Page No 317 (Sat May 01 00:00:00 EDT 2010)
- Volume (Year)
- 223 (2010)
- Product Usage
- -
Synergistic induction of local glucocorticoid generation by inflammatory cytokines and glucocorticoids: implications for inflammation associated bone loss.
- Authors
- Kaur K, Hardy R, Ahasan MM, Eijken M, van Leeuwen JP, Filer A, Thomas AM, Raza K, Buckley CD, Stewart PM, Rabbitt EH, Hewison M, Cooper MS
- Journal
- Ann Rheum Dis - Page No 1185 (Tue Jun 01 00:00:00 EDT 2010)
- Volume (Year)
- 69 (2010)
- Product Usage
- -
The role of reactive oxygen species in arsenite and monomethylarsonous acid-induced signal transduction in human bladder cells: acute studies.
- Authors
- Eblin KE, Hau AM, Jensen TJ, Futscher BW, Gandolfi AJ
- Journal
- Toxicology - Page No 47 (Tue Aug 19 00:00:00 EDT 2008)
- Volume (Year)
- 250 (2008)
- Product Usage
- -
Effect of n-3 polyunsaturated fatty acids on Barrett's epithelium in the human lower esophagus.
- Authors
- Mehta SP, Boddy AP, Cook J, Sams V, Lund EK, Johnson IT, Rhodes M
- Journal
- Am J Clin Nutr - Page No 949 (Tue Apr 01 00:00:00 EDT 2008)
- Volume (Year)
- 87 (2008)
- Product Usage
- -
Gene expression by human monocytes from peripheral blood in response to exposure to metals.
- Authors
- Jost-Albrecht K, Hofstetter W
- Journal
- J Biomed Mater Res B Appl Biomater - Page No 449 (Wed Feb 01 00:00:00 EST 2006)
- Volume (Year)
- 76 (2006)
- Product Usage
- -
Butein downregulates phorbol 12-myristate 13-acetate-induced COX-2 transcriptional activity in cancerous and non-cancerous breast cells.
- Authors
- Lau GT, Huang H, Lin SM, Leung LK
- Journal
- Eur J Pharmacol - Page No 24 (Wed Dec 01 00:00:00 EST 2010)
- Volume (Year)
- 648 (2010)
- Product Usage
- -
Effects of medroxyprogesterone acetate on gene expression in myometrial explants from pregnant women.
- Authors
- Cordeaux Y, Tattersall M, Charnock-Jones DS, Smith GC
- Journal
- J Clin Endocrinol Metab - Page No E437 (Wed Dec 01 00:00:00 EST 2010)
- Volume (Year)
- 95 (2010)
- Product Usage
- -
Modulation of cytokine-induced cyclooxygenase 2 expression by PPARG ligands through NFkappaB signal disruption in human WISH and amnion cells.
- Authors
- Ackerman WE 4th, Zhang XL, Rovin BH, Kniss DA
- Journal
- Biol Reprod - Page No 527 (Thu Sep 01 00:00:00 EDT 2005)
- Volume (Year)
- 73 (2005)
- Product Usage
- -
Cyclic stretch induces cyclooxygenase-2 gene expression in vascular endothelial cells via activation of nuclear factor kappa-beta.
- Authors
- Zhao H, Hiroi T, Hansen BS, Rade JJ
- Journal
- Biochem Biophys Res Commun - Page No 599 (Fri Nov 27 00:00:00 EST 2009)
- Volume (Year)
- 389 (2009)
- Product Usage
- -
Prostaglandin EP2 receptor expression is increased in Barrett's oesophagus and oesophageal adenocarcinoma.
- Authors
- Jimenez P, Piazuelo E, Cebrian C, Ortego J, Strunk M, Garcia-Gonzalez MA, Santander S, Alcedo J, Lanas A
- Journal
- Aliment Pharmacol Ther - Page No 440 (Mon Feb 01 00:00:00 EST 2010)
- Volume (Year)
- 31 (2010)
- Product Usage
- -
Social regulation of gene expression in human leukocytes.
- Authors
- Cole SW, Hawkley LC, Arevalo JM, Sung CY, Rose RM, Cacioppo JT
- Journal
- Genome Biol - Page No R189 (Mon Jan 01 00:00:00 EST 2007)
- Volume (Year)
- 8 (2007)
- Product Usage
- -
Coexpression of cyclooxygenases (COX-1, COX-2) and vascular endothelial growth factors (VEGF-A, VEGF-C) in esophageal adenocarcinoma.
- Authors
- von Rahden BH, Stein HJ, Puhringer F, Koch I, Langer R, Piontek G, Siewert JR, Hofler H, Sarbia M
- Journal
- Cancer Res - Page No 5038 (Wed Jun 15 00:00:00 EDT 2005)
- Volume (Year)
- 65 (2005)
- Product Usage
- -
Nuclear factor-kappa B regulates inducible prostaglandin E synthase expression in human amnion mesenchymal cells.
- Authors
- Ackerman WE 4th, Summerfield TL, Vandre DD, Robinson JM, Kniss DA
- Journal
- Biol Reprod - Page No 68 (Tue Jan 01 00:00:00 EST 2008)
- Volume (Year)
- 78 (2008)
- Product Usage
- -
