Hs00162669_m1

• Gene Symbol: TERT
• Gene Name: telomerase reverse transcriptase
• Gene Aliases: CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT
• Chromosome Location: Chr.5: 1253167 - 1295626 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: TERT
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_198253.2	NP_937983.2	11 - 12	2905		85
	XM_017009796.1	XP_016865285.1	11 - 12	3477		85
GenBank mRNA	AF015950.1	-	11 - 12	2902		85
	AF018167.1	-	11 - 12	2903		85
	AX810036.1	-	11 - 12	2902		85
	BC062321.1	-	7 - 8	1478		85
	JF896283.1	-	4 - 5	517		85

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0500009852.hg.1
This assay targets the same location as HTA transcript cluster(s) TC05001105.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Homo sapiens, Human Stem Cell Pluripotency, Inventoried, Human_Stem_Cell, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene TERT

Panther Classification:

Molecular Function -

DNA metabolism protein

Gene Ontology Categories:

Process(es)

telomere maintenance
transcription, RNA-templated
RNA-dependent DNA biosynthetic process
telomere maintenance via telomerase
mitochondrion organization
negative regulation of gene expression
DNA strand elongation
positive regulation of Wnt signaling pathway
production of siRNA involved in RNA interference
regulation of protein stability
positive regulation of protein binding
RNA biosynthetic process
positive regulation of hair cycle
positive regulation of nitric-oxide synthase activity
establishment of protein localization to telomere
cellular response to hypoxia
DNA biosynthetic process
replicative senescence
positive regulation of pri-miRNA transcription from RNA polymerase II promoter
negative regulation of production of siRNA involved in RNA interference
positive regulation of protein localization to nucleolus
beta-catenin-TCF complex assembly
positive regulation of stem cell proliferation
negative regulation of cellular senescence
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

tRNA binding
transcription coactivator binding
DNA binding
telomerase activity
telomerase RNA reverse transcriptase activity
RNA binding
RNA-directed DNA polymerase activity
RNA-directed RNA polymerase activity
protein binding
nucleotidyltransferase activity
telomeric DNA binding
protein homodimerization activity
metal ion binding
telomerase RNA binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR05016054.hg.1	TC05001105.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR05016054.hg.1	ENST00000296820.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05016054.hg.1	ENST00000310581.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05016054.hg.1	ENST00000334602.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05016054.hg.1	NM_001193376.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR05016054.hg.1	NM_198253.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500169520.hg.1	ENST00000310581.9	Ensembl
Affymetrix Human Clariom D Assay	PSR0500169520.hg.1	ENST00000334602.10	Ensembl
Affymetrix Human Clariom D Assay	PSR0500169520.hg.1	ENST00000460137.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0500169520.hg.1	ENST00000484238.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0500169520.hg.1	NM_001193376.1	Refseq
Affymetrix Human Clariom D Assay	PSR0500169520.hg.1	NM_198253.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500169520.hg.1	ENST00000310581.9	Ensembl
Affymetrix Human Clariom D Assay	PSR0500169520.hg.1	ENST00000334602.10	Ensembl
Affymetrix Human Clariom D Assay	PSR0500169520.hg.1	ENST00000460137.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0500169520.hg.1	ENST00000484238.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0500169520.hg.1	NM_001193376.1	Refseq
Affymetrix Human Clariom D Assay	PSR0500169520.hg.1	NM_198253.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500169520.hg.1	TC0500009852.hg.1	Clariom D TC