Assay Details

Gene Symbol: CYP1A2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_000761.4	NP_000752.2	2 - 3	895		67
GenBank mRNA	AF182274.1	-	1 - 2	839		67
	BC067424.1	-	2 - 3	875	7002123	67
	BC067425.1	-	2 - 3	875	7002124	67
	BC067426.1	-	2 - 3	875	7002125	67
	BC067427.1	-	2 - 3	875	7002126	67
	BC067428.1	-	2 - 3	875	7002128	67
	BC067429.1	-	2 - 3	875	7002129	67
	M55053.1	-	1 - 2	839		67
	Z00036.1	-	1 - 2	839		67

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1500007855.hg.1
This assay targets the same location as HTA transcript cluster(s) TC15000684.hg.1

Set Membership:

Ambion siRNA available

Amplicon length less than or equal to 70

Mammalian Gene Collection

P450

Recommended Assay

Homo sapiens

Human CYP450 and other Oxygenases

Human Immune Response

Inventoried

MicroArray Quality Control (MAQC)

Human_Immune

Human CYP450 + oxygenases

Human_CYP450_and_other_Oxygenases

Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene CYP1A2

Gene Ontology Categories:

Function(s) Process(es)

MicroArray Probes:

Affymetrix

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR15006009.hg.1	ENST00000343932.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR15006009.hg.1	NM_000761.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR15006009.hg.1	TC15000684.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	TC1500007855.hg.1	ENST00000343932.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1500007855.hg.1	ENST00000343932.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1500007855.hg.1	ENST00000343932.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1500007855.hg.1	ENST00000343932.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1500007855.hg.1	ENST00000343932.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1500007855.hg.1	ENST00000343932.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1500007855.hg.1	ENST00000343932.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1500007855.hg.1	ENST00000343932.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1500007855.hg.1	NM_000761.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1500007855.hg.1	NM_000761.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1500007855.hg.1	NM_000761.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1500007855.hg.1	NM_000761.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1500007855.hg.1	NM_000761.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1500007855.hg.1	NM_000761.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1500007855.hg.1	NM_000761.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1500007855.hg.1	NM_000761.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1500007855.hg.1	NM_000761.4	Refseq
Affymetrix Human Clariom D Assay	PSR1500156032.hg.1	ENST00000343932.4	Ensembl
Affymetrix Human Clariom D Assay	PSR1500156032.hg.1	NM_000761.4	Refseq
Affymetrix Human Clariom D Assay	PSR1500156032.hg.1	ENST00000343932.4	Ensembl
Affymetrix Human Clariom D Assay	PSR1500156032.hg.1	NM_000761.4	Refseq
Affymetrix Human Clariom D Assay	PSR1500156032.hg.1	TC1500007855.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	TC1500007855.hg.1	ENST00000343932.4	Ensembl
Affymetrix Human Clariom D Assay	TC1500007855.hg.1	ENST00000343932.4	Ensembl
Affymetrix Human Clariom D Assay	TC1500007855.hg.1	ENST00000343932.4	Ensembl
Affymetrix Human Clariom D Assay	TC1500007855.hg.1	ENST00000343932.4	Ensembl
Affymetrix Human Clariom D Assay	TC1500007855.hg.1	ENST00000343932.4	Ensembl
Affymetrix Human Clariom D Assay	TC1500007855.hg.1	ENST00000343932.4	Ensembl
Affymetrix Human Clariom D Assay	TC1500007855.hg.1	ENST00000343932.4	Ensembl
Affymetrix Human Clariom D Assay	TC1500007855.hg.1	ENST00000343932.4	Ensembl
Affymetrix Human Clariom D Assay	TC1500007855.hg.1	NM_000761.4	Refseq
Affymetrix Human Clariom D Assay	TC1500007855.hg.1	NM_000761.4	Refseq
Affymetrix Human Clariom D Assay	TC1500007855.hg.1	NM_000761.4	Refseq
Affymetrix Human Clariom D Assay	TC1500007855.hg.1	NM_000761.4	Refseq
Affymetrix Human Clariom D Assay	TC1500007855.hg.1	NM_000761.4	Refseq
Affymetrix Human Clariom D Assay	TC1500007855.hg.1	NM_000761.4	Refseq
Affymetrix Human Clariom D Assay	TC1500007855.hg.1	NM_000761.4	Refseq
Affymetrix Human Clariom D Assay	TC1500007855.hg.1	NM_000761.4	Refseq
Affymetrix Human Clariom D Assay	TC1500007855.hg.1	NM_000761.4	Refseq

Citations (6)

Aqueous extract from Spanish black radish (Raphanus sativus L. Var. niger) induces detoxification enzymes in the HepG2 human hepatoma cell line.

Authors: Hanlon PR, Webber DM, Barnes DM
Journal: J Agric Food Chem - Page No 6439 (Wed Aug 08 00:00:00 EDT 2007)
Volume (Year): 55 (2007)
Product Usage: -

Disturbed expression of phase I and phase II estrogen-metabolizing enzymes in endometrial cancer: lower levels of CYP1B1 and increased expression of S-COMT.

Authors: Hevir N, Sinkovec J, Rizner TL
Journal: Mol Cell Endocrinol - Page No 158 (Sat Jan 01 00:00:00 EST 2011)
Volume (Year): 331 (2011)
Product Usage: -

Development of stably transfected human and rat hepatoma cell lines for the species-specific assessment of xenobiotic response enhancer module (XREM)-dependent induction of drug metabolism.

Authors: Fery Y, Mueller SO, Schrenk D
Journal: Toxicology - Page No 11 (Tue Nov 09 00:00:00 EST 2010)
Volume (Year): 277 (2010)
Product Usage: -

The use of human hepatocytes to investigate drug metabolism and CYP enzyme induction.

Authors: Klieber S, Torreilles F, Guillou F, Fabre G
Journal: Methods Mol Biol - Page No 295 (Fri Jan 01 00:00:00 EST 2010)
Volume (Year): 640 (2010)
Product Usage: -

Robust expansion of human hepatocytes in Fah-/-/Rag2-/-/Il2rg-/- mice.

Authors: Azuma H, Paulk N, Ranade A, Dorrell C, Al-Dhalimy M, Ellis E, Strom S, Kay MA, Finegold M, Grompe M
Journal: Nat Biotechnol - Page No 903 (Wed Aug 01 00:00:00 EDT 2007)
Volume (Year): 25 (2007)
Product Usage: -

Simultaneous assessment of cytochrome P450 activity in cultured human hepatocytes for compound-mediated induction of CYP3A4, CYP2B6, and CYP1A2.

Authors: Rhodes SP, Otten JN, Hingorani GP, Hartley DP, Franklin RB
Journal: J Pharmacol Toxicol Methods - Page No (Wed Nov 24 00:00:00 EST 2010)
Volume (Year): (2010)
Product Usage: -

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