Assay Details

Gene Symbol: BAX
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001291428.1	NP_001278357.1	4 - 5	439		62
	NM_001291429.1	NP_001278358.1	3 - 4	387		62
	NM_001291430.1	NP_001278359.1	2 - 3	240		62
	NM_001291431.1	NP_001278360.1	2 - 3	240		62
	NM_004324.3	NP_004315.1	4 - 5	439		62
	NM_138761.3	NP_620116.1	4 - 5	439		62
	NM_138763.3	NP_620118.1	3 - 4	292		62
	NM_138764.4	NP_620119.2	4 - 5	439		62
	XM_017027077.1	XP_016882566.1	4 - 5	448		62
GenBank mRNA	AF247393.1	-	4 - 5	370		62
	AF250190.1	-	2 - 3	171		62
	AJ417988.1	-	3 - 4	349		62
	AJ586909.1	-	2 - 3	158		62
	AJ586910.1	-	3 - 4	305		62
	AK291076.1	-	4 - 5	419		62
	BC014175.2	-	4 - 5	422	4578562	62
	BM706954.1	-	2 - 3	252		62
	CN281003.1	-	4 - 5	392		62
	HQ889830.1	-	2 - 3	171		62
	JX524562.1	-	3 - 4	319		62
	KF830846.1	-	3 - 4	319		62
	KF830847.1	-	3 - 4	319		62
	KF830848.1	-	3 - 4	319		62
	L22473.1	-	4 - 5	370		62
	L22474.1	-	4 - 5	370		62
	U19599.1	-	3 - 4	223		62

More Information

Set Membership:

Amplicon length less than or equal to 70

Apoptosis

Immune Tolerance Network

Mammalian Gene Collection

Recommended Assay

Homo sapiens

Human Pathogenesis of ALS

Human Immune Response

Human c-Myc and Apoptosis

Human NGF Pathway

Human Apoptotic Pathways triggered by HIV1

Human p53 Signaling

Human Developmental Phases of Colorectal Cancer

HUMAN COLORECTAL CANCER METASTASIS

HUMAN MOLECULAR MECHANISMS OF CANCER

HUMAN APOPTOSIS THROUGH DEATH RECEPTORS

HUMAN P53 MEDIATED APOPTOSIS

HUMAN IL-6 PATHWAY

HUMAN CELLULAR APOPTOSIS PATHWAY

Inventoried

Human_c-Myc_and_Apoptosis

Human_Immune

Human_Developmental_Phases_of_Colorectal_Cancer

Human_Pathogenesis_of_ALS

Human_NGF_Pathway

Human_p53_Signaling

Human_Apoptotic_Pathways_Triggered_by_HIV1

Human_IL-6_Pathway

Human_Apoptosis_through_Death_Receptors

Human_Molecular_Mechanisms_of_Cancer

Human_p53_Mediated_Apoptosis

Human_Cellular_Apoptosis_Pathway

Human_Colorectal_Cancer_Metastasis

Probe spans exons

Gene Ontology Categories:

Function(s) Process(es)

Citations (15)

The synthetic liver X receptor agonist GW3965 reduces tissue factor production and inflammatory responses in human islets in vitro.

Authors: Scholz H, Lund T, Dahle MK, Collins JL, Korsgren O, Wang JE, Foss A
Journal: Diabetologia - Page No 1352 (Wed Jul 01 00:00:00 EDT 2009)
Volume (Year): 52 (2009)
Product Usage: -

MDM2-dependent inhibition of p53 is required for Epstein-Barr virus B-cell growth transformation and infected-cell survival.

Authors: Forte E, Luftig MA
Journal: J Virol - Page No 2491 (Sun Mar 01 00:00:00 EST 2009)
Volume (Year): 83 (2009)
Product Usage: -

Octreotide promotes apoptosis in human somatotroph tumor cells by activating somatostatin receptor type 2.

Authors: Ferrante E, Pellegrini C, Bondioni S, Peverelli E, Locatelli M, Gelmini P, Luciani P, Peri A, Mantovani G, Bosari S, Beck-Peccoz P, Spada A, Lania A
Journal: Endocr Relat Cancer - Page No 955 (Fri Sep 01 00:00:00 EDT 2006)
Volume (Year): 13 (2006)
Product Usage: -

Cell cycle arrest and proapoptotic effects of the anticancer cyclodepsipeptide serratamolide (AT514) are independent of p53 status in breast cancer cells.

Authors: Soto-Cerrato V, Montaner B, Martinell M, Vilaseca M, Giralt E, Perez-Tomas R
Journal: Biochem Pharmacol - Page No 32 (Mon Dec 19 00:00:00 EST 2005)
Volume (Year): 71 (2005)
Product Usage: -

Local erythropoietin and endothelial progenitor cells improve regional cardiac function in acute myocardial infarction.

Authors: Stein A, Knodler M, Makowski M, Kuhnel S, Nekolla S, Keithahn A, Weidl E, Groha P, Schurmann M, Saraste A, Botnar R, Oostendorp RA, Ott I
Journal: Bmc Cardiovasc Disord - Page No 43 (Fri Jan 01 00:00:00 EST 2010)
Volume (Year): 10 (2010)
Product Usage: -

Quantitative evaluation of the apoptosis regulating genes Survivin, Bcl-2 and Bax in inflammatory and malignant pleural lesions.

Authors: Falleni M, Pellegrini C, Marchetti A, Roncalli M, Nosotti M, Palleschi A, Santambrogio L, Coggi G, Bosari S
Journal: Lung Cancer - Page No 211 (Sun May 01 00:00:00 EDT 2005)
Volume (Year): 48 (2005)
Product Usage: -

The candidate tumor suppressor CST6 alters the gene expression profile of human breast carcinoma cells: down-regulation of the potent mitogenic, motogenic, and angiogenic factor autotaxin.

Authors: Song J, Jie C, Polk P, Shridhar R, Clair T, Zhang J, Yin L, Keppler D
Journal: Biochem Biophys Res Commun - Page No 175 (Fri Feb 03 00:00:00 EST 2006)
Volume (Year): 340 (2006)
Product Usage: -

High radiosensitivity of germ cells in human male fetus.

Authors: Lambrot R, Coffigny H, Pairault C, Lecureuil C, Frydman R, Habert R, Rouiller-Fabre V
Journal: J Clin Endocrinol Metab - Page No 2632 (Sun Jul 01 00:00:00 EDT 2007)
Volume (Year): 92 (2007)
Product Usage: -

DNA damage, DNA repair rates and mRNA expression levels of cell cycle genes (TP53, p21CDKN1A, BCL2 and BAX) with respect to occupational exposure to styrene.

Authors: Hanova M, Vodickova L, Vaclavikova R, Smerhovsky Z, Stetina R, Hlavac P, Naccarati A, Slyskova J, Polakova V, Soucek P, Kumar R, Hemminki K, Vodicka P
Journal: Carcinogenesis - Page No (Thu Oct 21 00:00:00 EDT 2010)
Volume (Year): (2010)
Product Usage: -

Bone morphogenetic proteins and receptors are over-expressed in bone-marrow cells of multiple myeloma patients and support myeloma cells by inducing ID genes.

Authors: Grcevic D, Kusec R, Kovacic N, Lukic A, Lukic IK, Ivcevic S, Nemet D, Seiwerth RS, Ostojic SK, Croucher PI, Marusic A
Journal: Leuk Res - Page No 742 (Tue Jun 01 00:00:00 EDT 2010)
Volume (Year): 34 (2010)
Product Usage: -

c-myc antisense oligonucleotides sensitize human colorectal cancer cells to chemotherapeutic drugs.

Authors: Abaza MS, Al-Saffar A, Al-Sawan S, Al-Attiyah R
Journal: Tumour Biol - Page No 287 (Tue Jan 01 00:00:00 EST 2008)
Volume (Year): 29 (2008)
Product Usage: -

IFNgamma restores breast cancer sensitivity to fulvestrant by regulating STAT1, IFN regulatory factor 1, NF-kappaB, BCL2 family members, and signaling to caspase-dependent apoptosis.

Authors: Ning Y, Riggins RB, Mulla JE, Chung H, Zwart A, Clarke R
Journal: Mol Cancer Ther - Page No 1274 (Sat May 01 00:00:00 EDT 2010)
Volume (Year): 9 (2010)
Product Usage: -

Delivery of small interfering RNA for inhibition of endothelial cell apoptosis by hypoxia and serum deprivation.

Authors: Cho SW, Hartle L, Son SM, Yang F, Goldberg M, Xu Q, Langer R, Anderson DG
Journal: Biochem Biophys Res Commun - Page No 158 (Fri Nov 07 00:00:00 EST 2008)
Volume (Year): 376 (2008)
Product Usage: -

Modeled gravitational unloading triggers differentiation and apoptosis in preosteoclastic cells.

Authors: Monici M, Fusi F, Paglierani M, Marziliano N, Cogoli A, Pratesi R, Bernabei PA
Journal: J Cell Biochem - Page No 65 (Mon May 01 00:00:00 EDT 2006)
Volume (Year): 98 (2006)
Product Usage: -

Activated protein C N-linked glycans modulate cytoprotective signaling function on endothelial cells.

Authors: Ni Ainle F, O'Donnell JS, Johnson JA, Brown L, Gleeson EM, Smith OP, Preston RJ
Journal: J Biol Chem - Page No (Tue Nov 02 00:00:00 EDT 2010)
Volume (Year): (2010)
Product Usage: -

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System Message

Genomic Map

Assay Details

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Citations (15)

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