Hs00233632_m1

• Gene Symbol: FMR1
• Gene Name: fragile X mental retardation 1
• Gene Aliases: FMRP, FRAXA, POF, POF1
• Chromosome Location: Chr.X: 147911951 - 147951127 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: FMR1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001185075.1	NP_001172004.1	12 - 13	1416		81
	NM_002024.5	NP_002015.1	12 - 13	1416		81
	NR_033699.1		12 - 13	1416		81
GenBank mRNA	KJ534837.1	-	12 - 13	1187		81
	KM091457.1	-	13 - 14	1295		81
	KM091459.1	-	13 - 14	1295		81
	S65791.1	-	12 - 13	1406		81
	X69962.1	-	12 - 13	1406		81

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0X00008668.hg.1
This assay targets the same location as HTA transcript cluster(s) TC0X000705.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Apoptosis, Immune Tolerance Network, Homo sapiens, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene FMR1

Panther Classification:

Molecular Function -

translation factor

Gene Ontology Categories:

Process(es)

regulation of alternative mRNA splicing, via spliceosome
positive regulation of receptor internalization
mRNA processing
cellular response to DNA damage stimulus
glutamate receptor signaling pathway
RNA splicing
negative regulation of translation
gene silencing by RNA
positive regulation of histone phosphorylation
cellular response to UV
regulation of mRNA stability
modulation by host of viral RNA genome replication
positive regulation of translation
negative regulation of translational initiation
regulation of neurotransmitter secretion
mRNA transport
regulation of filopodium assembly
positive regulation of filopodium assembly
regulation of gene silencing by miRNA
regulation of dendritic spine development
positive regulation of dendritic spine development
cellular response to hydroxyurea
cellular response to virus
regulation of neuronal action potential
negative regulation of long term synaptic depression
positive regulation of intracellular transport of viral material
negative regulation of voltage-gated calcium channel activity
positive regulation of proteasomal protein catabolic process
positive regulation of mRNA binding
negative regulation of synaptic vesicle exocytosis
positive regulation of gene silencing by miRNA
negative regulation of cytoplasmic translation
positive regulation of response to DNA damage stimulus

Function(s)

G-quadruplex RNA binding
chromatin binding
RNA binding
mRNA binding
mRNA 3'-UTR binding
protein binding
microtubule binding
poly(U) RNA binding
translation repressor activity
translation initiation factor binding
RNA strand annealing activity
poly(G) binding
methylated histone binding
siRNA binding
miRNA binding
RNA stem-loop binding
identical protein binding
protein homodimerization activity
ribosome binding
ion channel binding
poly(A) RNA binding
dynein binding
protein heterodimerization activity
mRNA 5'-UTR binding
sequence-specific mRNA binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR0X009025.hg.1	TC0X000705.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR0X009025.hg.1	ENST00000218200.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR0X009025.hg.1	ENST00000370470.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR0X009025.hg.1	ENST00000370471.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR0X009025.hg.1	ENST00000370475.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR0X009025.hg.1	ENST00000370477.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR0X009025.hg.1	ENST00000439526.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR0X009025.hg.1	ENST00000440235.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR0X009025.hg.1	ENST00000492846.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR0X009025.hg.1	NM_001185075.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR0X009025.hg.1	NM_001185076.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR0X009025.hg.1	NM_001185081.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR0X009025.hg.1	NM_001185082.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR0X009025.hg.1	NM_002024.5	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR0X009025.hg.1	NR_033699.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR0X009025.hg.1	NR_033700.1	Refseq
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000218200.12	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000370470.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000370471.7	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000370475.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000370477.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000439526.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000440235.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000492846.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000611273.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000616382.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000620828.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000621453.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	NM_001185075.1	Refseq
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	NM_001185076.1	Refseq
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	NM_001185081.1	Refseq
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	NM_001185082.1	Refseq
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	NM_002024.5	Refseq
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	NR_033699.1	Refseq
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	NR_033700.1	Refseq
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000218200.12	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000370470.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000370471.7	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000370475.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000370477.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000439526.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000440235.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000492846.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000611273.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000616382.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000620828.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	ENST00000621453.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	NM_001185075.1	Refseq
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	NM_001185076.1	Refseq
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	NM_001185081.1	Refseq
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	NM_001185082.1	Refseq
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	NM_002024.5	Refseq
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	NR_033699.1	Refseq
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	NR_033700.1	Refseq
Affymetrix Human Clariom D Assay	PSR0X00158702.hg.1	TC0X00008668.hg.1	Clariom D TC