Hs00241091_m1

• Gene Symbol: TSC2
• Gene Name: tuberous sclerosis 2
• Gene Aliases: LAM, PPP1R160, TSC4
• Chromosome Location: Chr.16: 2047804 - 2088720 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: TSC2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_000548.4	NP_000539.2	26 - 27	3165		90
	NM_001114382.2	NP_001107854.1	26 - 27	3165		90
	XM_011522636.2	XP_011520938.1	26 - 27	3052		90
	XM_011522638.2	XP_011520940.2	25 - 26	3145		90
	XM_017023618.1	XP_016879107.1	27 - 28	3139		90
GenBank mRNA	BC150300.1	-	26 - 27	3040	8860381	90
	KJ535094.1	-	10 - 11	1151		90
	X75621.1	-	25 - 26	2983		90

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1600006587.hg.1
This assay targets the same location as HTA transcript cluster(s) TC16000059.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Homo sapiens, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene TSC2

Panther Classification:

Molecular Function -

GTPase-activating protein

Gene Ontology Categories:

Process(es)

neural tube closure
negative regulation of protein kinase activity
protein import into nucleus
endocytosis
cell cycle arrest
heart development
protein localization
negative regulation of cell proliferation
negative regulation of phosphatidylinositol 3-kinase signaling
viral process
vesicle-mediated transport
regulation of endocytosis
negative regulation of Wnt signaling pathway
negative regulation of TOR signaling
protein kinase B signaling
positive regulation of GTPase activity
regulation of insulin receptor signaling pathway
negative regulation of insulin receptor signaling pathway
insulin-like growth factor receptor signaling pathway
positive chemotaxis
regulation of small GTPase mediated signal transduction
regulation of cell cycle
negative regulation of protein kinase B signaling

Function(s)

GTPase activator activity
protein binding
phosphatase binding
small GTPase binding
protein homodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR16001256.hg.1	ENST00000219476.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR16001256.hg.1	ENST00000350773.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR16001256.hg.1	ENST00000353929.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR16001256.hg.1	ENST00000382538.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR16001256.hg.1	ENST00000401874.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR16001256.hg.1	ENST00000439673.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR16001256.hg.1	NM_000548.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR16001256.hg.1	NM_001077183.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR16001256.hg.1	NM_001114382.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR16001256.hg.1	TC16000059.hg.1	HTA TC
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000219476.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000350773.8	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000382538.10	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000401874.6	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000439117.6	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000439673.6	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000471143.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000483020.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000497886.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000561695.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000568366.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000568454.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	NM_000548.4	Refseq
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	NM_001077183.2	Refseq
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	NM_001114382.2	Refseq
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000219476.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000350773.8	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000382538.10	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000401874.6	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000439117.6	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000439673.6	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000471143.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000483020.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000497886.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000561695.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000568366.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	ENST00000568454.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	NM_000548.4	Refseq
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	NM_001077183.2	Refseq
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	NM_001114382.2	Refseq
Affymetrix Human Clariom D Assay	PSR1600146237.hg.1	TC1600006587.hg.1	Clariom D TC