Hs00269575_s1

• Gene Symbol: SOCS3
• Gene Name: suppressor of cytokine signaling 3
• Gene Aliases: ATOD4, CIS3, Cish3, SOCS-3, SSI-3, SSI3
• Chromosome Location: Chr.17: 78356777 - 78360079 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: SOCS3
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_003955.4	NP_003946.3	2	523		101
GenBank mRNA	AB004904.1	-	1	211		101
	AB006967.1	-	1	105		101
	AF159854.1	-	1	105		101
	AK314212.1	-	2	521		101
	BC060858.1	-	2	521	30333577	101
	BT019544.1	-	1	105		101
	CR536497.1	-	1	105		101
	CR541694.1	-	1	105		101
	DA671124.1	-	2	523		101

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1700011903.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Apoptosis, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Inventoried, Both primers and probe map within a single exon

Matching Ambion siRNAs:

Click here to find siRNAs for Gene SOCS3

Panther Classification:

Molecular Function -

kinase modulator

Gene Ontology Categories:

Process(es)

response to hypoxia
negative regulation of protein kinase activity
JAK-STAT cascade
aging
response to heat
response to gamma radiation
protein ubiquitination
cytokine-mediated signaling pathway
organ regeneration
response to food
response to estradiol
response to lipopolysaccharide
response to progesterone
response to insulin
regulation of growth
response to drug
negative regulation of tyrosine phosphorylation of Stat1 protein
positive regulation of tyrosine phosphorylation of Stat3 protein
negative regulation of tyrosine phosphorylation of Stat3 protein
negative regulation of apoptotic process
positive regulation of cell differentiation
negative regulation of JAK-STAT cascade
negative regulation of insulin receptor signaling pathway
negative regulation of inflammatory response
response to glucocorticoid
regulation of interferon-gamma-mediated signaling pathway
branching involved in labyrinthine layer morphogenesis
placenta blood vessel development
trophoblast giant cell differentiation
spongiotrophoblast differentiation

Function(s)

protein kinase inhibitor activity
protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	ENST00000587578.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	ENST00000587578.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	ENST00000587578.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	PSR1700197041.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	PSR1700197041.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	PSR1700197041.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	PSR1700197041.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	PSR1700197041.hg.1	TC1700011903.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	ENST00000587578.1	Ensembl
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	ENST00000587578.1	Ensembl
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	ENST00000587578.1	Ensembl
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	NM_003955.4	Refseq