Hs00329015_s1

• Gene Symbol: MAP2K6
• Gene Name: mitogen-activated protein kinase kinase 6
• Gene Aliases: MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3
• Chromosome Location: Chr.17: 69414697 - 69553854 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: MAP2K6
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	XM_005257515.2	XP_005257572.1	12	12022		83
	XM_005257516.2	XP_005257573.1	12	11895		83
	XM_006721975.3	XP_006722038.1	12	11923		83
	XM_011525025.2	XP_011523327.1	12	12309		83
	XM_011525026.2	XP_011523328.1	12	11770		83
	XM_011525027.2	XP_011523329.1	12	11685		83

Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Transcript Location	Amplicon Length
GenBankmRNA	AW516870.1	-	1	251		Chr. 17 - 69552168 - 69552671 [+] on Build GRCh38	83
GenBankmRNA	BI918782.1	-	1	399		Chr. 17 - 69552044 - 69552846 [+] on Build GRCh38	83
GenBankmRNA	BC037328.1	-	1	1061		Chr. 17 - 69551358 - 69553861 [+] on Build GRCh38	83
GenBankmRNA	BF694748.1	-		420		Chr. - - [-] on Build	83
GenBankmRNA	BM811540.1	-	1	183		Chr. 17 - 69552244 - 69553130 [+] on Build GRCh38	83
GenBankmRNA	AW956269.1	-	1	359		Chr. 17 - 69552060 - 69552621 [+] on Build GRCh38	83
GenBankmRNA	DA893572.1	-	1	49		Chr. 17 - 69552370 - 69552891 [+] on Build GRCh38	83

Adjacent Gene Details

	Gene name	Gene Symbol	Alias	Distance	Relative Direction	Location Chromsome
Upstream	ATP binding cassette subfamily A member 5	ABCA5	ABC13, EST90625	-214.5kb	Anti-sense	Chr. 17 - 69244435 - 69327182 on NCBI Build GRCh38
Downstream	long intergenic non-protein coding RNA 1483	LINC01483		40.1kb	Sense	Chr. 17 - 69593987 - 69903000 on NCBI Build GRCh38

More Information

Additional Information:

Based on assay re-evaluation, this assay may detect genomic DNA. Please contact Tech Support if you need more information.

• Set Membership: Amplicon length between 71 and 85, 3' Most, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Both primers and probe map within a single exon

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPK activity
response to ischemia
transcription, DNA-templated
regulation of transcription, DNA-templated
apoptotic process
DNA damage induced protein phosphorylation
cell cycle arrest
signal transduction
peptidyl-tyrosine phosphorylation
ovulation cycle process
positive regulation of prostaglandin secretion
proteolysis in other organism
response to drug
positive regulation of apoptotic process
positive regulation of nitric-oxide synthase biosynthetic process
cardiac muscle contraction
nucleotide-binding oligomerization domain containing signaling pathway
cellular response to sorbitol

Function(s)

receptor signaling protein serine/threonine kinase activity
MAP kinase kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
protein kinase binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	TC1700008761.hg.1	ENST00000588041.1	Ensembl
Affymetrix Human Clariom D Assay	TC1700008761.hg.1	ENST00000588041.1	Ensembl