Hs00366247_g1

• Gene Symbol: MADD
• Gene Name: MAP kinase activating death domain
• Gene Aliases: DENN, IG20, RAB3GEP
• Chromosome Location: Chr.11: 47269376 - 47330031 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: MADD
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001135943.1	NP_001129415.1	24 - 25	3952		82
	NM_001135944.1	NP_001129416.1	24 - 25	3919		82
	NM_003682.3	NP_003673.3	27 - 28	4237		82
	NM_130470.2	NP_569826.2	24 - 25	4226		82
	NM_130471.2	NP_569827.2	25 - 26	3991		82
	NM_130472.2	NP_569828.2	24 - 25	3931		82
	NM_130473.2	NP_569829.2	25 - 26	4120		82
	NM_130474.2	NP_569830.2	24 - 25	3931		82
	NM_130475.2	NP_569831.1	27 - 28	4261		82
	NM_130476.2	NP_569832.2	24 - 25	4081		82
	XM_005253189.2	XP_005253246.1	27 - 28	4261		82
	XM_005253196.2	XP_005253253.1	25 - 26	4144		82
	XM_005253199.2	XP_005253256.1	24 - 25	4084		82
	XM_005253200.2	XP_005253257.1	27 - 28	4258		82
	XM_005253201.2	XP_005253258.1	25 - 26	4015		82
	XM_005253203.2	XP_005253260.1	24 - 25	3955		82
	XM_005253204.2	XP_005253261.1	24 - 25	3943		82
	XM_005253205.1	XP_005253262.1	24 - 25	3955		82
	XM_017018478.1	XP_016873967.1	27 - 28	4249		82
	XM_017018479.1	XP_016873968.1	26 - 27	4195		82
	XM_017018480.1	XP_016873969.1	25 - 26	4141		82
	XM_017018481.1	XP_016873970.1	25 - 26	4135		82
	XM_017018482.1	XP_016873971.1	25 - 26	4132		82
	XM_017018483.1	XP_016873972.1	27 - 28	4120		82
	XM_017018484.1	XP_016873973.1	24 - 25	4072		82
	XM_017018485.1	XP_016873974.1	24 - 25	4033		82
	XM_017018486.1	XP_016873975.1	26 - 27	4066		82
	XM_017018487.1	XP_016873976.1	26 - 27	4060		82
	XM_017018488.1	XP_016873977.1	27 - 28	4249		82
	XM_017018489.1	XP_016873978.1	27 - 28	4210		82
	XM_017018490.1	XP_016873979.1	26 - 27	4194		82
	XM_017018491.1	XP_016873980.1	26 - 27	4160		82
	XM_017018492.1	XP_016873981.1	26 - 27	4195		82
	XM_017018493.1	XP_016873982.1	26 - 27	4176		82
	XM_017018494.1	XP_016873983.1	25 - 26	4147		82
	XM_017018495.1	XP_016873984.1	25 - 26	4144		82
	XM_017018496.1	XP_016873985.1	25 - 26	4091		82
	XM_017018497.1	XP_016873986.1	25 - 26	4096		82
	XM_017018498.1	XP_016873987.1	27 - 28	4120		82
	XM_017018499.1	XP_016873988.1	27 - 28	4089		82
	XM_017018500.1	XP_016873989.1	24 - 25	4081		82
	XM_017018501.1	XP_016873990.1	26 - 27	4034		82
	XM_017018502.1	XP_016873991.1	26 - 27	4047		82
	XM_017018503.1	XP_016873992.1	26 - 27	4031		82
	XM_017018504.1	XP_016873993.1	26 - 27	4044		82
	XM_017018505.1	XP_016873994.1	26 - 27	4022		82
	XM_017018506.1	XP_016873995.1	26 - 27	4027		82
	XM_017018507.1	XP_016873996.1	26 - 27	4047		82
	XM_017018508.1	XP_016873997.1	25 - 26	4018		82
	XM_017018509.1	XP_016873998.1	25 - 26	3971		82
	XM_017018510.1	XP_016873999.1	25 - 26	4006		82
GenBank mRNA	AB002356.1	-	27 - 28	4233		82
	AF440100.1	-	27 - 28	4211		82
	AF440101.1	-	25 - 26	4094		82
	AF440102.1	-	25 - 26	3965		82
	AF440103.1	-	24 - 25	3905		82
	AF440434.1	-	24 - 25	3905		82
	AK292442.1	-	24 - 25	3883		82
	AK308780.1	-	8 - 9	689		82
	BC040484.1	-	24 - 25	3936	5271798	82
	U44953.1	-	24 - 25	4045		82
	U77352.1	-	24 - 25	4194		82

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1100007473.hg.1
This assay targets the same location as HTA transcript cluster(s) TC11000406.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene MADD

Gene Ontology Categories:

Process(es)

activation of MAPK activity
cell surface receptor signaling pathway
regulation of tumor necrosis factor-mediated signaling pathway
regulation of Rab protein signal transduction
regulation of apoptotic process
positive regulation of GTPase activity
regulation of cell cycle
execution phase of apoptosis
regulation of extrinsic apoptotic signaling pathway via death domain receptors
regulation of extrinsic apoptotic signaling pathway

Function(s)

death receptor binding
protein binding
Rab guanyl-nucleotide exchange factor activity
protein kinase activator activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	ENST00000311027.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	ENST00000342922.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	ENST00000349238.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	ENST00000395336.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	ENST00000395342.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	ENST00000395344.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	ENST00000402192.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	ENST00000402799.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	ENST00000405573.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	ENST00000406482.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	ENST00000407859.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	NM_001135943.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	NM_001135944.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	NM_003682.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	NM_130470.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	NM_130471.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	NM_130472.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	NM_130473.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	NM_130474.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	NM_130475.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	NM_130476.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR11005271.hg.1	TC11000406.hg.1	HTA TC
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	ENST00000311027.9	Ensembl
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	ENST00000342922.8	Ensembl
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	ENST00000349238.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	ENST00000395336.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	ENST00000395344.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	ENST00000402192.6	Ensembl
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	ENST00000402799.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	ENST00000405573.2	Ensembl
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	ENST00000406482.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	ENST00000407859.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	NM_001135943.1	Refseq
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	NM_001135944.1	Refseq
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	NM_003682.3	Refseq
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	NM_130470.2	Refseq
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	NM_130471.2	Refseq
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	NM_130472.2	Refseq
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	NM_130473.2	Refseq
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	NM_130474.2	Refseq
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	NM_130475.2	Refseq
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	NM_130476.2	Refseq
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	ENST00000311027.9	Ensembl
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	ENST00000342922.8	Ensembl
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	ENST00000349238.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	ENST00000395336.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	ENST00000395344.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	ENST00000402192.6	Ensembl
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	ENST00000402799.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	ENST00000405573.2	Ensembl
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	ENST00000406482.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	ENST00000407859.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	NM_001135943.1	Refseq
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	NM_001135944.1	Refseq
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	NM_003682.3	Refseq
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	NM_130470.2	Refseq
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	NM_130471.2	Refseq
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	NM_130472.2	Refseq
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	NM_130473.2	Refseq
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	NM_130474.2	Refseq
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	NM_130475.2	Refseq
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	NM_130476.2	Refseq
Affymetrix Human Clariom D Assay	PSR1100153258.hg.1	TC1100007473.hg.1	Clariom D TC