Hs00367107_m1

• Gene Symbol: SOCS5
• Gene Name: suppressor of cytokine signaling 5
• Gene Aliases: CIS6, CISH6, Cish5, SOCS-5
• Chromosome Location: Chr.2: 46698960 - 46762788 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: SOCS5
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_014011.4	NP_054730.1	1 - 2	147		110
GenBank mRNA	AB014571.1	-	1 - 2	155		110
	AK290194.1	-	1 - 2	161		110
	AL136896.1	-	1 - 2	147		110

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0200007477.hg.1
This assay targets the same location as HTA transcript cluster(s) TC02000286.hg.1

Additional Information:

This assay is in the 5'UTR region of the AB014571.1,AK290194.1,AL136896.1,NM_014011.4 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Homo sapiens, Human IL-9 PATHWAY, HUMAN IL-6 PATHWAY, Inventoried, Human_IL-9_Pathway, Human_IL-6_Pathway, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene SOCS5

Panther Classification:

Molecular Function -

kinase modulator

Gene Ontology Categories:

Process(es)

epidermal growth factor receptor signaling pathway
negative regulation of epidermal growth factor-activated receptor activity
JAK-STAT cascade
negative regulation of signal transduction
cell growth
protein ubiquitination
cytokine-mediated signaling pathway
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
negative regulation of interleukin-6 production
regulation of growth
positive regulation of T-helper 1 cell differentiation
negative regulation of T-helper 2 cell differentiation
negative regulation of JAK-STAT cascade
negative regulation of inflammatory response
negative regulation of monocyte chemotactic protein-1 production
negative regulation of endothelial cell activation

Function(s)

protein kinase inhibitor activity
epidermal growth factor receptor binding
protein binding
receptor tyrosine kinase binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	TC0900009160.hg.1	ENST00000449637.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900009160.hg.1	ENST00000449637.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900009160.hg.1	ENST00000449637.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900009160.hg.1	ENST00000449637.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900009160.hg.1	ENST00000449637.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200007477.hg.1	ENST00000306503.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200007477.hg.1	ENST00000306503.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200007477.hg.1	ENST00000306503.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200007477.hg.1	ENST00000306503.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200007477.hg.1	ENST00000306503.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200007477.hg.1	ENST00000306503.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200007477.hg.1	ENST00000394861.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200007477.hg.1	ENST00000394861.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200007477.hg.1	ENST00000394861.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200007477.hg.1	ENST00000394861.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200007477.hg.1	NM_014011.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200007477.hg.1	NM_014011.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200007477.hg.1	NM_014011.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200007477.hg.1	NM_014011.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200007477.hg.1	NM_014011.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200007477.hg.1	NM_144949.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200007477.hg.1	NM_144949.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200007477.hg.1	NM_144949.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200007477.hg.1	NM_144949.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200007477.hg.1	NM_144949.2	Refseq
Affymetrix Human Clariom D Assay	TC0900009160.hg.1	ENST00000449637.1	Ensembl
Affymetrix Human Clariom D Assay	TC0900009160.hg.1	ENST00000449637.1	Ensembl
Affymetrix Human Clariom D Assay	TC0900009160.hg.1	ENST00000449637.1	Ensembl
Affymetrix Human Clariom D Assay	TC0900009160.hg.1	ENST00000449637.1	Ensembl
Affymetrix Human Clariom D Assay	TC0900009160.hg.1	ENST00000449637.1	Ensembl