Hs00374471_m1

• Gene Symbol: ARHGEF6
• Gene Name: Rac/Cdc42 guanine nucleotide exchange factor 6
• Gene Aliases: COOL2, Cool-2, MRX46, PIXA, alpha-PIX, alphaPIX
• Chromosome Location: Chr.X: 136665547 - 136781656 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: ARHGEF6
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001306177.1	NP_001293106.1	13 - 14	1555		90
	NM_004840.2	NP_004831.1	14 - 15	2017		90
	XM_005262499.2	XP_005262556.1	14 - 15	2329		90
	XM_011531412.2	XP_011529714.1	15 - 16	2410		90
	XM_011531413.1	XP_011529715.1	14 - 15	2329		90
	XM_011531414.1	XP_011529716.1	14 - 15	2329		90
	XM_011531415.2	XP_011529717.1	14 - 15	1765		90
	XM_011531416.2	XP_011529718.1	14 - 15	2028		90
	XM_011531417.1	XP_011529719.1	13 - 14	1947		90
	XM_017029975.1	XP_016885464.1	15 - 16	2410		90
	XM_017029976.1	XP_016885465.1	13 - 14	1947		90
GenBank mRNA	AK291742.1	-	14 - 15	1560		90
	AK294929.1	-	13 - 14	1361		90
	AK295709.1	-	14 - 15	1637		90
	BC033768.1	-	2 - 3	188		90
	BC039856.1	-	14 - 15	2017	4510206	90
	BC043505.1	-	13 - 14	1521	6015396	90
	BX537390.1	-	14 - 15	1622		90
	D13631.1	-	6 - 7	595		90
	D25304.1	-	14 - 15	1548		90

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0X00010933.hg.1
This assay targets the same location as HTA transcript cluster(s) TC0X001416.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene ARHGEF6

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

apoptotic process
JNK cascade
lamellipodium assembly
regulation of Rho protein signal transduction
positive regulation of apoptotic process
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction

Function(s)

guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
GTPase activator activity
protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR0X018822.hg.1	TC0X001416.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR0X018822.hg.1	ENST00000250617.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR0X018822.hg.1	ENST00000370620.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR0X018822.hg.1	ENST00000370622.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR0X018822.hg.1	ENST00000535227.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR0X018822.hg.1	ENST00000535736.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR0X018822.hg.1	NM_004840.2	Refseq
Affymetrix Human Clariom D Assay	PSR0X00174296.hg.1	ENST00000250617.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00174296.hg.1	ENST00000370620.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00174296.hg.1	ENST00000370622.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00174296.hg.1	NM_001306177.1	Refseq
Affymetrix Human Clariom D Assay	PSR0X00174296.hg.1	NM_004840.2	Refseq
Affymetrix Human Clariom D Assay	PSR0X00174296.hg.1	ENST00000250617.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00174296.hg.1	ENST00000370620.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00174296.hg.1	ENST00000370622.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00174296.hg.1	NM_001306177.1	Refseq
Affymetrix Human Clariom D Assay	PSR0X00174296.hg.1	NM_004840.2	Refseq
Affymetrix Human Clariom D Assay	PSR0X00174296.hg.1	TC0X00010933.hg.1	Clariom D TC