Hs00374476_m1

• Gene Symbol: ARHGEF6
• Gene Name: Rac/Cdc42 guanine nucleotide exchange factor 6
• Gene Aliases: COOL2, Cool-2, MRX46, PIXA, alpha-PIX, alphaPIX
• Chromosome Location: Chr.X: 136665547 - 136781656 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: ARHGEF6
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001306177.1	NP_001293106.1	18 - 19	2035		130
	NM_004840.2	NP_004831.1	19 - 20	2497		130
	XM_005262499.2	XP_005262556.1	17 - 18	2662		130
	XM_011531412.2	XP_011529714.1	20 - 21	2890		130
	XM_011531413.1	XP_011529715.1	19 - 20	2821		130
	XM_011531414.1	XP_011529716.1	18 - 19	2800		130
	XM_011531415.2	XP_011529717.1	19 - 20	2245		130
	XM_011531416.2	XP_011529718.1	19 - 20	2508		130
	XM_011531417.1	XP_011529719.1	18 - 19	2439		130
	XM_017029975.1	XP_016885464.1	20 - 21	2902		130
	XM_017029976.1	XP_016885465.1	16 - 17	2280		130
GenBank mRNA	AK291742.1	-	19 - 20	2040		130
	AK294929.1	-	18 - 19	1841		130
	AK295709.1	-	19 - 20	2117		130
	BC033768.1	-	7 - 8	668		130
	BC039856.1	-	19 - 20	2497	4510206	130
	BC043505.1	-	18 - 19	2001	6015396	130
	BX537390.1	-	19 - 20	2102		130
	D13631.1	-	11 - 12	1075		130
	D25304.1	-	19 - 20	2028		130

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0X00010933.hg.1
This assay targets the same location as HTA transcript cluster(s) TC0X001416.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene ARHGEF6

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

apoptotic process
JNK cascade
lamellipodium assembly
regulation of Rho protein signal transduction
positive regulation of apoptotic process
positive regulation of GTPase activity
regulation of small GTPase mediated signal transduction

Function(s)

guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
GTPase activator activity
protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR0X018816.hg.1	TC0X001416.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR0X018816.hg.1	ENST00000250617.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR0X018816.hg.1	ENST00000370620.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR0X018816.hg.1	ENST00000370622.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR0X018816.hg.1	ENST00000535227.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR0X018816.hg.1	ENST00000535736.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR0X018816.hg.1	NM_004840.2	Refseq
Affymetrix Human Clariom D Assay	PSR0X00174291.hg.1	ENST00000250617.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00174291.hg.1	ENST00000370620.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00174291.hg.1	ENST00000370622.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00174291.hg.1	NM_001306177.1	Refseq
Affymetrix Human Clariom D Assay	PSR0X00174291.hg.1	NM_004840.2	Refseq
Affymetrix Human Clariom D Assay	PSR0X00174291.hg.1	ENST00000250617.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00174291.hg.1	ENST00000370620.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00174291.hg.1	ENST00000370622.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0X00174291.hg.1	NM_001306177.1	Refseq
Affymetrix Human Clariom D Assay	PSR0X00174291.hg.1	NM_004840.2	Refseq
Affymetrix Human Clariom D Assay	PSR0X00174291.hg.1	TC0X00010933.hg.1	Clariom D TC