Hs00377721_m1

• Gene Symbol: PTGS1
• Gene Name: prostaglandin-endoperoxide synthase 1
• Gene Aliases: COX1, COX3, PCOX1, PES-1, PGG/HS, PGHS-1, PGHS1, PHS1, PTGHS
• Chromosome Location: Chr.9: 122369906 - 122395703 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: PTGS1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_000962.3	NP_000953.2	2 - 3	172		123
	NM_001271164.1	NP_001258093.1	2 - 3	172		123
	NM_080591.2	NP_542158.1	2 - 3	172		123
GenBank mRNA	AK290022.1	-	2 - 3	125		123
	BC029840.1	-	2 - 3	144	5174923	123
	CD014048.1	-	2 - 3	138		123
	DA392280.1	-	2 - 3	172		123
	M59979.1	-	1 - 2	97		123
	S36219.1	-	1 - 2	92		123
	S36271.1	-	1 - 2	92		123
	S78220.1	-	1 - 2	92		123

More Information

Updated Mapping Information

This assay targets the same location as HTA transcript cluster(s) TC09000614.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Homo sapiens, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene PTGS1

Panther Classification:

Molecular Function -

oxygenase

Gene Ontology Categories:

Process(es)

prostaglandin biosynthetic process
lipid metabolic process
xenobiotic metabolic process
inflammatory response
response to oxidative stress
aging
learning
memory
regulation of blood pressure
response to organonitrogen compound
negative regulation of norepinephrine secretion
sensory perception of pain
cyclooxygenase pathway
negative regulation of epinephrine secretion
maintenance of blood-brain barrier
regulation of cell proliferation
positive regulation of vasoconstriction
positive regulation of smooth muscle contraction
response to corticosterone
oxidation-reduction process
response to fatty acid
cellular oxidant detoxification

Function(s)

peroxidase activity
prostaglandin-endoperoxide synthase activity
lipid binding
heme binding
metal ion binding
dioxygenase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR09007093.hg.1	TC09000614.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR09007093.hg.1	ENST00000223423.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR09007093.hg.1	ENST00000362012.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR09007093.hg.1	ENST00000540753.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR09007093.hg.1	NM_000962.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR09007093.hg.1	NM_080591.2	Refseq