Hs00394225_g1

• Gene Symbol: CHD8
• Gene Name: chromodomain helicase DNA binding protein 8
• Gene Aliases: AUTS18, HELSNF1
• Chromosome Location: Chr.14: 21385194 - 21437298 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: CHD8
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001170629.1	NP_001164100.1	32 - 33	6532		76
	NM_020920.3	NP_065971.2	33 - 34	5777		76
GenBank mRNA	AB046784.3	-	32 - 33	6020		76
	AK056639.1	-	13 - 14	2399		76
	AK131077.1	-	18 - 19	3356		76
	BC011695.2	-	1 - 2	78		76
	BC025964.1	-	1 - 2	78		76
	BC063693.1	-	1 - 2	96		76
	BC073903.1	-	2 - 3	202		76
	BC098452.1	-	7 - 8	1448		76
	CR749315.1	-	33 - 34	5722		76

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1400008631.hg.1
This assay targets the same location as HTA transcript cluster(s) TC14000917.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene CHD8

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
in utero embryonic development
transcription, DNA-templated
brain development
covalent chromatin modification
negative regulation of Wnt signaling pathway
DNA duplex unwinding
ATP-dependent chromatin remodeling
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
positive regulation of transcription from RNA polymerase III promoter
digestive tract development
canonical Wnt signaling pathway
negative regulation of canonical Wnt signaling pathway
negative regulation of fibroblast apoptotic process

Function(s)

p53 binding
DNA binding
DNA helicase activity
chromatin binding
protein binding
ATP binding
beta-catenin binding
DNA-dependent ATPase activity
methylated histone binding
histone binding
armadillo repeat domain binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR14009996.hg.1	ENST00000262707.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR14009996.hg.1	ENST00000399982.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR14009996.hg.1	ENST00000430710.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR14009996.hg.1	ENST00000557364.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR14009996.hg.1	NM_001170629.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR14009996.hg.1	NM_020920.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR14009996.hg.1	TC14000917.hg.1	HTA TC
Affymetrix Human Clariom D Assay	PSR1400162338.hg.1	ENST00000399982.6	Ensembl
Affymetrix Human Clariom D Assay	PSR1400162338.hg.1	ENST00000430710.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1400162338.hg.1	ENST00000553870.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1400162338.hg.1	ENST00000557364.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1400162338.hg.1	NM_001170629.1	Refseq
Affymetrix Human Clariom D Assay	PSR1400162338.hg.1	NM_020920.3	Refseq
Affymetrix Human Clariom D Assay	PSR1400162338.hg.1	ENST00000399982.6	Ensembl
Affymetrix Human Clariom D Assay	PSR1400162338.hg.1	ENST00000430710.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1400162338.hg.1	ENST00000553870.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1400162338.hg.1	ENST00000557364.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1400162338.hg.1	NM_001170629.1	Refseq
Affymetrix Human Clariom D Assay	PSR1400162338.hg.1	NM_020920.3	Refseq
Affymetrix Human Clariom D Assay	PSR1400162338.hg.1	TC1400008631.hg.1	Clariom D TC