Hs00400446_m1

• Gene Symbol: GRB2
• Gene Name: growth factor receptor bound protein 2
• Gene Aliases: ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2
• Chromosome Location: Chr.17: 75318076 - 75405709 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: GRB2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_002086.4	NP_002077.1	4 - 5	653		83
GenBank mRNA	AF498925.1	-	3 - 4	296		83
	AK091010.1	-	4 - 5	1081		83
	AK315565.1	-	4 - 5	649		83
	BC000631.2	-	4 - 5	598	3345524	83
	BI459414.1	-	4 - 5	660		83
	CR450363.1	-	3 - 4	296		83
	CR541942.1	-	3 - 4	296		83
	M96995.1	-	3 - 4	374		83
	X62852.1	-	1 - 2	125		83

More Information

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene GRB2

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

MAPK cascade
epidermal growth factor receptor signaling pathway
Ras protein signal transduction
cell-cell signaling
axon guidance
insulin receptor signaling pathway
fibroblast growth factor receptor signaling pathway
positive regulation of signal transduction
regulation of phosphatidylinositol 3-kinase signaling
viral process
positive regulation of actin filament polymerization
T cell costimulation
receptor internalization
phosphatidylinositol-3-phosphate biosynthetic process
Fc-epsilon receptor signaling pathway
Fc-gamma receptor signaling pathway involved in phagocytosis
ERBB2 signaling pathway
negative regulation of epidermal growth factor receptor signaling pathway
signal transduction in response to DNA damage
regulation of MAPK cascade
positive regulation of GTPase activity
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
anatomical structure formation involved in morphogenesis
leukocyte migration
branching involved in labyrinthine layer morphogenesis
cellular response to ionizing radiation
positive regulation of reactive oxygen species metabolic process

Function(s)

SH3/SH2 adaptor activity
Ras guanyl-nucleotide exchange factor activity
epidermal growth factor receptor binding
neurotrophin TRKA receptor binding
protein binding
1-phosphatidylinositol-3-kinase activity
SH3 domain binding
protein kinase binding
protein phosphatase binding
identical protein binding
insulin receptor substrate binding
poly(A) RNA binding
ephrin receptor binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity