Hs00608289_m1

• Gene Symbol: ALK
• Gene Name: anaplastic lymphoma receptor tyrosine kinase
• Gene Aliases: CD246, NBLST3
• Chromosome Location: Chr.2: 29192774 - 29921611 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: ALK
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_004304.4	NP_004295.2	24 - 25	4694		71
GenBank mRNA	AB209477.4	-	24 - 25	4231		71
	EU788003.1	-	24 - 25	4649		71
	EU788004.1	-	24 - 25	4649		71
	EU788005.1	-	24 - 25	4649		71
	EU788006.1	-	24 - 25	4649		71
	EU788007.1	-	24 - 25	4649		71
	EU788008.1	-	24 - 25	4649		71
	EU788009.1	-	24 - 25			71
	EU788010.1	-	24 - 25	4649		71
	FJ838786.1	-	24 - 25	4649		71
	FJ838787.1	-	24 - 25	4649		71
	GU128152.1	-	24 - 25	3742		71
	GU128153.1	-	24 - 25	3742		71
	GU128154.1	-	24 - 25	3742		71
	GU128155.1	-	24 - 25	3742		71
	GU128156.1	-	24 - 25	3742		71
	GU128157.1	-	24 - 25			71
	LN864494.1	-	5 - 6	942		71
	U62540.1	-	24 - 25	4653		71
	U66559.1	-	24 - 25	3890		71

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0200012140.hg.1
This assay targets the same location as HTA transcript cluster(s) TC02001708.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Protein Kinase, Homo sapiens, Human Protein Kinase Pathways, Inventoried, Human_Protein_Kinase, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene ALK

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

activation of MAPK activity
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
cell proliferation
phosphorylation
peptidyl-tyrosine phosphorylation
NIK/NF-kappaB signaling
regulation of apoptotic process
protein autophosphorylation
neuron development
positive regulation of NF-kappaB transcription factor activity

Function(s)

NF-kappaB-inducing kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
protein binding
ATP binding
identical protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR02027475.hg.1	TC02001708.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR02027475.hg.1	ENST00000389048.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02027475.hg.1	NM_004304.4	Refseq
Affymetrix Human Clariom D Assay	PSR0200188574.hg.1	ENST00000389048.7	Ensembl
Affymetrix Human Clariom D Assay	PSR0200188574.hg.1	ENST00000431873.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0200188574.hg.1	ENST00000618119.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0200188574.hg.1	NM_004304.4	Refseq
Affymetrix Human Clariom D Assay	PSR0200188574.hg.1	ENST00000389048.7	Ensembl
Affymetrix Human Clariom D Assay	PSR0200188574.hg.1	ENST00000431873.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0200188574.hg.1	ENST00000618119.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0200188574.hg.1	NM_004304.4	Refseq
Affymetrix Human Clariom D Assay	PSR0200188574.hg.1	TC0200012140.hg.1	Clariom D TC