Hs00609060_m1

• Gene Symbol: BRCA2
• Gene Name: BRCA2, DNA repair associated
• Gene Aliases: BRCC2, BROVCA2, FACD, FAD, FAD1, FANCD, FANCD1, GLM3, PNCA2, XRCC11
• Chromosome Location: Chr.13: 32315480 - 32399672 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: BRCA2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_000059.3	NP_000050.2	13 - 14	7236		126
GenBank mRNA	DQ897648.1	-	12 - 13	7009		126
	U43746.1	-	13 - 14	7237		126

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1300006802.hg.1
This assay targets the same location as HTA transcript cluster(s) TC13000111.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Homo sapiens, Human Androgen Panel, Inventoried, MicroArray Quality Control (MAQC), Human_Androgen, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene BRCA2

Panther Classification:

Molecular Function -

damaged DNA-binding protein

Gene Ontology Categories:

Process(es)

telomere maintenance via recombination
double-strand break repair via homologous recombination
DNA synthesis involved in DNA repair
strand displacement
cytokinesis
oocyte maturation
inner cell mass cell proliferation
nucleotide-excision repair
double-strand break repair
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
male meiosis I
spermatogenesis
brain development
cell aging
response to nutrient
female gonad development
response to X-ray
response to UV-C
response to gamma radiation
hemopoiesis
mammary gland development
chromosome breakage
homologous chromosome orientation involved in meiotic metaphase I plate congression
response to estradiol
regulation of cytokinesis
negative regulation of mammary gland epithelial cell proliferation
multicellular organism growth
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
histone H3 acetylation
histone H4 acetylation
positive regulation of transcription, DNA-templated
positive regulation of mitotic cell cycle
replication fork protection
centrosome duplication
establishment of protein localization to telomere
mitotic recombination-dependent replication fork processing

Function(s)

protease binding
single-stranded DNA binding
histone acetyltransferase activity
protein binding
H3 histone acetyltransferase activity
H4 histone acetyltransferase activity
gamma-tubulin binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR13001173.hg.1	ENST00000544455.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR13001173.hg.1	NM_000059.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR13001173.hg.1	ENST00000380152.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR13001173.hg.1	TC13000111.hg.1	HTA TC
Affymetrix Human Clariom D Assay	PSR1300146304.hg.1	ENST00000380152.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1300146304.hg.1	ENST00000544455.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1300146304.hg.1	ENST00000614259.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1300146304.hg.1	NM_000059.3	Refseq
Affymetrix Human Clariom D Assay	PSR1300146304.hg.1	ENST00000380152.7	Ensembl
Affymetrix Human Clariom D Assay	PSR1300146304.hg.1	ENST00000544455.5	Ensembl
Affymetrix Human Clariom D Assay	PSR1300146304.hg.1	ENST00000614259.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1300146304.hg.1	NM_000059.3	Refseq
Affymetrix Human Clariom D Assay	PSR1300146304.hg.1	TC1300006802.hg.1	Clariom D TC