Hs00610318_m1

• Gene Symbol: TGFBR1
• Gene Name: transforming growth factor beta receptor 1
• Gene Aliases: AAT5, ACVRLK4, ALK-5, ALK5, ESS1, LDS1, LDS1A, LDS2A, MSSE, SKR4, TGFR-1, tbetaR-I
• Chromosome Location: Chr.9: 99104038 - 99154192 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: TGFBR1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_004612.3	NP_004603.1	2 - 3	453		92
	XM_011518949.2	XP_011517251.1	2 - 3	308		92
GenBank mRNA	AJ619020.1	-	1 - 2	157		92
	AK302059.1	-	2 - 3	453		92
	AK302234.1	-	2 - 3	326		92
	L11695.1	-	2 - 3	412		92

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0900008202.hg.1
This assay targets the same location as HTA transcript cluster(s) TC09000500.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Protein Kinase, Homo sapiens, Human IL-2 Gene Expression in Activated and Quiescent T-Cell, HUMAN COLORECTAL CANCER METASTASIS, HUMAN MOLECULAR MECHANISMS OF CANCER, HUMAN SMAD SIGNALING NETWORK, HUMAN PKA SIGNALING, HUMAN P53 MEDIATED APOPTOSIS, HUMAN FACTORS PROMOTING CARDIOGENESIS IN VERTEBRATES, HUMAN PANCREATIC ADENOCARCINOMA, Inventoried, Human_IL-2_Gene_Expression_in_Activated_and_Quiescent_T-Cells, Human_Pancreatic_Adenocarcinoma, Human_Factors_Promoting_Cardiogenesis_in_Vertebrates, Human_PKA_Signaling, Human_Molecular_Mechanisms_of_Cancer, Human_p53_Mediated_Apoptosis, Human_Colorectal_Cancer_Metastasis, Human_SMAD_Signaling_Network, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene TGFBR1

Panther Classification:

Molecular Function -

serine/threonine protein kinase receptor

Gene Ontology Categories:

Process(es)

activation of MAPKK activity
skeletal system development
angiogenesis
in utero embryonic development
kidney development
blastocyst development
epithelial to mesenchymal transition
negative regulation of endothelial cell proliferation
positive regulation of endothelial cell proliferation
lens development in camera-type eye
ventricular trabecula myocardium morphogenesis
ventricular compact myocardium morphogenesis
proepicardium development
regulation of transcription, DNA-templated
protein phosphorylation
apoptotic process
cell cycle arrest
signal transduction
transforming growth factor beta receptor signaling pathway
heart development
positive regulation of cell proliferation
germ cell migration
male gonad development
post-embryonic development
anterior/posterior pattern specification
regulation of epithelial to mesenchymal transition
positive regulation of epithelial to mesenchymal transition
positive regulation of pathway-restricted SMAD protein phosphorylation
peptidyl-serine phosphorylation
peptidyl-threonine phosphorylation
signal transduction by protein phosphorylation
collagen fibril organization
positive regulation of cell growth
positive regulation of cell migration
negative regulation of transforming growth factor beta receptor signaling pathway
regulation of protein ubiquitination
negative regulation of chondrocyte differentiation
activin receptor signaling pathway
intracellular signal transduction
wound healing
endothelial cell activation
extracellular structure organization
regulation of protein binding
endothelial cell migration
positive regulation of transcription, DNA-templated
thymus development
neuron fate commitment
embryonic cranial skeleton morphogenesis
skeletal system morphogenesis
mesenchymal cell differentiation
artery morphogenesis
cell motility
positive regulation of cellular component movement
positive regulation of filopodium assembly
positive regulation of stress fiber assembly
positive regulation of protein kinase B signaling
parathyroid gland development
palate development
pharyngeal system development
regulation of cardiac muscle cell proliferation
cardiac epithelial to mesenchymal transition
pathway-restricted SMAD protein phosphorylation
positive regulation of SMAD protein import into nucleus
ventricular septum morphogenesis
coronary artery morphogenesis
response to cholesterol
cellular response to transforming growth factor beta stimulus
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation
positive regulation of occluding junction disassembly
positive regulation of apoptotic signaling pathway
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

protein kinase activity
protein serine/threonine kinase activity
receptor signaling protein serine/threonine kinase activity
transforming growth factor beta-activated receptor activity
transforming growth factor beta receptor activity, type I
receptor signaling protein activity
type II transforming growth factor beta receptor binding
protein binding
ATP binding
growth factor binding
SMAD binding
metal ion binding
transforming growth factor beta binding
I-SMAD binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374990.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374990.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374990.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374990.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374990.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374990.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374990.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374990.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374990.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374990.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374990.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374990.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374990.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374990.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374994.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374994.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374994.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374994.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374994.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374994.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374994.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374994.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374994.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374994.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374994.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374994.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374994.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374994.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374994.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000374994.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000546584.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000546584.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000546584.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000547314.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000547314.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000547314.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000547314.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000548365.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000548365.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000548365.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000548365.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000549021.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000549021.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000549021.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000549021.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000549021.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000549766.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000549766.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000549766.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000549766.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000549766.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000549766.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000549766.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000549766.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000549766.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000549766.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000549766.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000549766.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000550253.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000550253.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000550253.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000550253.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000550253.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000550253.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000550253.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000550253.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000550253.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000550253.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000550253.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000552516.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000552516.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000552516.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000552516.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000552516.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000552516.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000552516.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000552516.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000552516.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000552516.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000552516.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000552516.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000552516.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000552516.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000552573.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000552573.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	ENST00000552573.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001130916.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001130916.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001130916.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001130916.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001130916.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001130916.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001130916.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001130916.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001130916.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001130916.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001130916.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001130916.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001130916.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001130916.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001130916.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001306210.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001306210.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001306210.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001306210.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001306210.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001306210.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001306210.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001306210.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001306210.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001306210.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001306210.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001306210.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001306210.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001306210.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001306210.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_001306210.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_004612.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_004612.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_004612.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_004612.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_004612.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_004612.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_004612.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_004612.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_004612.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_004612.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_004612.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_004612.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_004612.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_004612.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_004612.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0900008202.hg.1	NM_004612.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1900009436.hg.1	ENST00000594355.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1900009436.hg.1	ENST00000594355.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1900009436.hg.1	ENST00000594355.1	Ensembl
Affymetrix Human Clariom D Assay	TC1900009436.hg.1	ENST00000594355.1	Ensembl
Affymetrix Human Clariom D Assay	TC1900009436.hg.1	ENST00000594355.1	Ensembl
Affymetrix Human Clariom D Assay	TC1900009436.hg.1	ENST00000594355.1	Ensembl