Hs00697016_m1

• Gene Symbol: BRAF
• Gene Name: B-Raf proto-oncogene, serine/threonine kinase
• Gene Aliases: B-RAF1, B-raf, BRAF1, NS7, RAFB1
• Chromosome Location: Chr.7: 140719331 - 140924764 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: BRAF
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_004333.4	NP_004324.2	9 - 10	1244		146
	XM_005250045.2	XP_005250102.1	9 - 10	1191		146
GenBank mRNA	AK314346.1	-	9 - 10	1191		146
	BC101757.1	-	9 - 10	1205	8069263	146
	BC112079.1	-	9 - 10	1205	8327547	146
	M95712.2	-	9 - 10	1244		146

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0700013629.hg.1
This assay targets the same location as HTA transcript cluster(s) TC07001927.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Apoptosis, Protein Kinase, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene BRAF

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPKK activity
myeloid progenitor cell differentiation
protein phosphorylation
visual learning
organ morphogenesis
positive regulation of gene expression
negative regulation of fibroblast migration
glucose transport
thyroid gland development
positive regulation of peptidyl-serine phosphorylation
somatic stem cell population maintenance
cellular response to drug
regulation of cell proliferation
negative regulation of apoptotic process
CD4-positive, alpha-beta T cell differentiation
positive T cell selection
response to peptide hormone
negative regulation of neuron apoptotic process
thymus development
positive regulation of axon regeneration
positive regulation of axonogenesis
protein heterooligomerization
positive regulation of stress fiber assembly
response to cAMP
long-term synaptic potentiation
head morphogenesis
face development
positive regulation of ERK1 and ERK2 cascade
cellular response to calcium ion
establishment of protein localization to membrane
positive regulation of substrate adhesion-dependent cell spreading
negative regulation of synaptic vesicle exocytosis
negative regulation of endothelial cell apoptotic process

Function(s)

protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
calcium ion binding
protein binding
ATP binding
small GTPase binding
mitogen-activated protein kinase kinase binding
identical protein binding
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR07029950.hg.1	TC07001927.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR07029950.hg.1	ENST00000288602.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR07029950.hg.1	NM_004333.5	Refseq
Affymetrix Human Clariom D Assay	PSR0700202210.hg.1	ENST00000288602.10	Ensembl
Affymetrix Human Clariom D Assay	PSR0700202210.hg.1	ENST00000497784.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0700202210.hg.1	NM_004333.5	Refseq
Affymetrix Human Clariom D Assay	PSR0700202210.hg.1	ENST00000288602.10	Ensembl
Affymetrix Human Clariom D Assay	PSR0700202210.hg.1	ENST00000497784.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0700202210.hg.1	NM_004333.5	Refseq
Affymetrix Human Clariom D Assay	PSR0700202210.hg.1	TC0700013629.hg.1	Clariom D TC