Hs00741684_g1

• Gene Symbol: PYCARD
• Gene Name: PYD and CARD domain containing
• Gene Aliases: ASC, CARD5, TMS, TMS-1, TMS1
• Chromosome Location: Chr.16: 31201486 - 31202776 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: PYCARD
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_145182.2	NP_660183.1	1 - 2	363		159
GenBank mRNA	AF255794.1	-	1 - 2	351		159

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1600010011.hg.1
This assay targets the same location as HTA transcript cluster(s) TC16001052.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Apoptosis, Protease, 3' Most, Detect Genomic DNA, Homo sapiens, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene PYCARD

Panther Classification:

Molecular Function -

protease

Gene Ontology Categories:

Process(es)

myeloid dendritic cell activation
activation of innate immune response
myeloid dendritic cell activation involved in immune response
positive regulation of antigen processing and presentation of peptide antigen via MHC class II
positive regulation of adaptive immune response
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
inflammatory response
signal transduction
regulation of tumor necrosis factor-mediated signaling pathway
positive regulation of actin filament polymerization
regulation of protein stability
negative regulation of NF-kappaB transcription factor activity
negative regulation of interferon-beta production
positive regulation of interferon-gamma production
positive regulation of interleukin-6 production
positive regulation of tumor necrosis factor production
tumor necrosis factor-mediated signaling pathway
positive regulation of activated T cell proliferation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
positive regulation of apoptotic process
negative regulation of I-kappaB kinase/NF-kappaB signaling
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
macropinocytosis
innate immune response
positive regulation of JNK cascade
positive regulation of interleukin-1 beta secretion
positive regulation of phagocytosis
defense response to Gram-negative bacterium
positive regulation of T cell activation
positive regulation of sequence-specific DNA binding transcription factor activity
positive regulation of NF-kappaB transcription factor activity
defense response to virus
positive regulation of ERK1 and ERK2 cascade
cellular response to lipopolysaccharide
cellular response to interleukin-1
cellular response to tumor necrosis factor
negative regulation of protein serine/threonine kinase activity
intrinsic apoptotic signaling pathway by p53 class mediator
positive regulation of chemokine secretion
positive regulation of release of cytochrome c from mitochondria
positive regulation of T cell migration
positive regulation of interleukin-8 secretion
positive regulation of interleukin-6 secretion
positive regulation of cysteine-type endopeptidase activity
positive regulation of interleukin-10 secretion
positive regulation of extrinsic apoptotic signaling pathway
regulation of intrinsic apoptotic signaling pathway

Function(s)

protease binding
interleukin-6 receptor binding
protein binding
tropomyosin binding
cysteine-type endopeptidase activator activity involved in apoptotic process
myosin I binding
enzyme binding
Pyrin domain binding
identical protein binding
protein homodimerization activity
BMP receptor binding
cysteine-type endopeptidase activity involved in apoptotic process

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR16015024.hg.1	ENST00000247470.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR16015024.hg.1	ENST00000350605.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR16015024.hg.1	ENST00000355986.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR16015024.hg.1	NM_013258.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR16015024.hg.1	NM_145182.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR16015024.hg.1	TC16001052.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000247470.9	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000247470.9	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000247470.9	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000247470.9	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000247470.9	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000247470.9	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000247470.9	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000247470.9	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000350605.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000350605.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000350605.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000350605.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000350605.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000561508.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000561508.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000561508.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000561508.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000561508.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000561508.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000561508.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000565022.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000565022.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000565022.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000565022.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	ENST00000565022.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	NM_013258.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	NM_013258.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	NM_013258.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	NM_013258.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	NM_013258.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	NM_013258.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	NM_145182.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	NM_145182.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	NM_145182.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	NM_145182.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1600010011.hg.1	NM_145182.2	Refseq
Affymetrix Human Clariom D Assay	PSR1600177481.hg.1	ENST00000247470.9	Ensembl
Affymetrix Human Clariom D Assay	PSR1600177481.hg.1	ENST00000350605.4	Ensembl
Affymetrix Human Clariom D Assay	PSR1600177481.hg.1	ENST00000565022.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1600177481.hg.1	NM_013258.4	Refseq
Affymetrix Human Clariom D Assay	PSR1600177481.hg.1	NM_145182.2	Refseq
Affymetrix Human Clariom D Assay	PSR1600177481.hg.1	ENST00000247470.9	Ensembl
Affymetrix Human Clariom D Assay	PSR1600177481.hg.1	ENST00000350605.4	Ensembl
Affymetrix Human Clariom D Assay	PSR1600177481.hg.1	ENST00000565022.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1600177481.hg.1	NM_013258.4	Refseq
Affymetrix Human Clariom D Assay	PSR1600177481.hg.1	NM_145182.2	Refseq
Affymetrix Human Clariom D Assay	PSR1600177481.hg.1	TC1600010011.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	PSR1600177480.hg.1	ENST00000247470.9	Ensembl
Affymetrix Human Clariom D Assay	PSR1600177480.hg.1	ENST00000350605.4	Ensembl
Affymetrix Human Clariom D Assay	PSR1600177480.hg.1	ENST00000565022.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1600177480.hg.1	NM_013258.4	Refseq
Affymetrix Human Clariom D Assay	PSR1600177480.hg.1	NM_145182.2	Refseq
Affymetrix Human Clariom D Assay	PSR1600177480.hg.1	ENST00000247470.9	Ensembl
Affymetrix Human Clariom D Assay	PSR1600177480.hg.1	ENST00000350605.4	Ensembl
Affymetrix Human Clariom D Assay	PSR1600177480.hg.1	ENST00000565022.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1600177480.hg.1	NM_013258.4	Refseq
Affymetrix Human Clariom D Assay	PSR1600177480.hg.1	NM_145182.2	Refseq
Affymetrix Human Clariom D Assay	PSR1600177480.hg.1	TC1600010011.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000247470.9	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000247470.9	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000247470.9	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000247470.9	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000247470.9	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000247470.9	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000247470.9	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000247470.9	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000350605.4	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000350605.4	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000350605.4	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000350605.4	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000350605.4	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000561508.1	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000561508.1	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000561508.1	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000561508.1	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000561508.1	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000561508.1	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000561508.1	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000565022.1	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000565022.1	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000565022.1	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000565022.1	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	ENST00000565022.1	Ensembl
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	NM_013258.4	Refseq
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	NM_013258.4	Refseq
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	NM_013258.4	Refseq
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	NM_013258.4	Refseq
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	NM_013258.4	Refseq
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	NM_013258.4	Refseq
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	NM_145182.2	Refseq
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	NM_145182.2	Refseq
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	NM_145182.2	Refseq
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	NM_145182.2	Refseq
Affymetrix Human Clariom D Assay	TC1600010011.hg.1	NM_145182.2	Refseq

Array Name	Probe IDs	Targets	Target Type
ABI Human Genome Survey Microarray Version 2.0	174254	-	-