Hs00893124_m1

• Gene Symbol: SOS1
• Gene Name: SOS Ras/Rac guanine nucleotide exchange factor 1
• Gene Aliases: GF1, GGF1, GINGF, HGF, NS4
• Chromosome Location: Chr.2: 38981549 - 39124959 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: SOS1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_005633.3	NP_005624.2	10 - 11	1897		132
	XM_005264515.4	XP_005264572.1	10 - 11	2126		132
	XM_011533062.2	XP_011531364.1	10 - 11	2065		132
	XM_011533064.2	XP_011531366.1	10 - 11	1805		132
	XM_011533066.2	XP_011531368.1	3 - 4	806		132
GenBank mRNA	AB209140.1	-	3 - 4	868		132
	AK290228.1	-	11 - 12	1943		132
	L13857.1	-	10 - 11	1856		132

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0200012307.hg.1
This assay targets the same location as HTA transcript cluster(s) TC02001761.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene SOS1

Panther Classification:

Molecular Function -

guanyl-nucleotide exchange factor

Gene Ontology Categories:

Process(es)

MAPK cascade
B cell homeostasis
hair follicle development
cardiac atrium morphogenesis
pericardium morphogenesis
signal transduction
epidermal growth factor receptor signaling pathway
Ras protein signal transduction
vitellogenesis
axon guidance
insulin receptor signaling pathway
regulation of T cell differentiation in thymus
regulation of Rho protein signal transduction
multicellular organism growth
Fc-epsilon receptor signaling pathway
ERBB2 signaling pathway
regulation of T cell proliferation
positive regulation of apoptotic process
positive regulation of GTPase activity
positive regulation of epidermal growth factor receptor signaling pathway
neurotrophin TRK receptor signaling pathway
blood vessel morphogenesis
leukocyte migration
regulation of small GTPase mediated signal transduction
positive regulation of small GTPase mediated signal transduction
palate development
eyelid development in camera-type eye
heart trabecula morphogenesis
midbrain morphogenesis
regulation of pro-B cell differentiation

Function(s)

DNA binding
guanyl-nucleotide exchange factor activity
Ras guanyl-nucleotide exchange factor activity
Rho guanyl-nucleotide exchange factor activity
GTPase activator activity
protein binding
SH3 domain binding
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000395038.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000402219.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000426016.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000451331.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000451331.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000451331.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000451331.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000461545.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000461545.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000461545.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000461545.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000469581.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000469581.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000469581.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000472480.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000472480.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000474390.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000474390.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000474390.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	ENST00000474390.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0200012307.hg.1	NM_005633.3	Refseq