Hs00894716_m1

• Gene Symbol: PTPRC
• Gene Name: protein tyrosine phosphatase, receptor type C
• Gene Aliases: B220, CD45, CD45R, GP180, L-CA, LCA, LY5, T200
• Chromosome Location: Chr.1: 198638968 - 198757476 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: PTPRC
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_002838.4	NP_002829.3	17 - 18	2070		119
	NM_080921.3	NP_563578.2	14 - 15	1587		119
	XM_006711472.3	XP_006711535.1	16 - 17	1887		119
	XM_006711473.3	XP_006711536.1	16 - 17	1815		119
	XM_006711474.3	XP_006711537.1	15 - 16	1671		119
GenBank mRNA	AK292131.1	-	14 - 15	1460		119
	AK299986.1	-	16 - 17	1745		119
	AK303539.1	-	17 - 18	1943		119
	AK307635.1	-	16 - 17	1804		119
	AK308217.1	-	15 - 16	1676		118
	BC014239.2	-	16 - 17	1790		119
	Y00062.1	-	15 - 16	1514		119
	Y00638.1	-	17 - 18	1937		119

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0100011105.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Homo sapiens, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene PTPRC

Panther Classification:

Molecular Function -

protein phosphatase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

negative regulation of T cell mediated cytotoxicity
negative regulation of cytokine-mediated signaling pathway
hematopoietic progenitor cell differentiation
immunoglobulin biosynthetic process
negative regulation of protein kinase activity
protein dephosphorylation
negative regulation of cell adhesion involved in substrate-bound cell migration
cell surface receptor signaling pathway
dephosphorylation
T cell differentiation
positive regulation of B cell proliferation
peptidyl-tyrosine dephosphorylation
B cell proliferation
positive regulation of T cell proliferation
cell cycle phase transition
positive regulation of protein kinase activity
bone marrow development
stem cell development
T cell receptor signaling pathway
B cell receptor signaling pathway
positive regulation of antigen receptor-mediated signaling pathway
release of sequestered calcium ion into cytosol
defense response to virus
regulation of cell cycle
positive regulation of hematopoietic stem cell migration
positive regulation of stem cell proliferation

Function(s)

protein tyrosine phosphatase activity
transmembrane receptor protein tyrosine phosphatase activity
protein binding
protein kinase binding