Hs00903127_m1

• Gene Symbol: VEGFA
• Gene Name: vascular endothelial growth factor A
• Gene Aliases: MVCD1, VEGF, VPF
• Chromosome Location: Chr.6: 43770209 - 43786487 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: VEGFA
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001025366.2	NP_001020537.2	5 - 6	1467		102
	NM_001025367.2	NP_001020538.2	5 - 6	1467		102
	NM_001171623.1	NP_001165094.1	5 - 6	1467		102
	NM_001171624.1	NP_001165095.1	5 - 6	1467		102
	NM_001171625.1	NP_001165096.1	5 - 6	1467		102
	NM_001204384.1	NP_001191313.1	5 - 6	1467		102
	NM_001204385.1	NP_001191314.1	5 - 6	1467		102
	NM_003376.5	NP_003367.4	5 - 6	1467		102
GenBank mRNA	AF062645.1	-	2 - 3	90		102
	AJ010438.1	-	5 - 6	429		102
	M27281.1	-	5 - 6	585		102
	S85192.1	-	5 - 6	497		102

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0600008109.hg.1
This assay targets the same location as HTA transcript cluster(s) TC06000608.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene VEGFA

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
angiogenesis
ovarian follicle development
patterning of blood vessels
vasculogenesis
response to hypoxia
in utero embryonic development
kidney development
positive regulation of protein phosphorylation
positive regulation of endothelial cell proliferation
cell migration involved in sprouting angiogenesis
positive regulation of neuroblast proliferation
positive regulation of mesenchymal cell proliferation
positive regulation of receptor internalization
platelet degranulation
positive regulation of leukocyte migration
heart morphogenesis
outflow tract morphogenesis
coronary vein morphogenesis
nervous system development
mesoderm development
lactation
positive regulation of cell proliferation
regulation of cell shape
positive regulation of endothelial cell migration
positive regulation of gene expression
monocyte differentiation
macrophage differentiation
lung development
positive regulation of cell migration
regulation of cGMP metabolic process
epithelial cell differentiation
positive regulation of vascular endothelial growth factor receptor signaling pathway
post-embryonic camera-type eye development
positive regulation of protein complex assembly
positive regulation of protein autophosphorylation
activation of protein kinase activity
positive regulation of CREB transcription factor activity
positive regulation of peptidyl-serine phosphorylation
tube formation
endothelial cell chemotaxis
cellular response to vascular endothelial growth factor stimulus
lymph vessel morphogenesis
positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway
VEGF-activated neuropilin signaling pathway
growth
eye photoreceptor cell development
positive regulation of tyrosine phosphorylation of Stat3 protein
negative regulation of apoptotic process
surfactant homeostasis
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of MAP kinase activity
positive regulation of blood vessel endothelial cell migration
positive regulation of angiogenesis
positive regulation of cell adhesion
positive regulation of transcription from RNA polymerase II promoter
vascular endothelial growth factor receptor signaling pathway
cell maturation
camera-type eye morphogenesis
cardiac muscle fiber development
branching morphogenesis of an epithelial tube
positive regulation of axon extension involved in axon guidance
artery morphogenesis
positive regulation of epithelial cell proliferation
positive regulation of peptidyl-tyrosine phosphorylation
positive chemotaxis
positive regulation of positive chemotaxis
induction of positive chemotaxis
positive regulation of cellular component movement
positive regulation of cell division
positive regulation of focal adhesion assembly
primitive erythrocyte differentiation
mammary gland alveolus development
cardiac vascular smooth muscle cell development
coronary artery morphogenesis
regulation of transcription from RNA polymerase II promoter in response to hypoxia
positive regulation of transcription from RNA polymerase II promoter in response to hypoxia
cellular response to hypoxia
dopaminergic neuron differentiation
commissural neuron axon guidance
positive regulation of protein kinase C signaling
positive regulation of cell migration involved in sprouting angiogenesis
positive regulation of branching involved in ureteric bud morphogenesis
regulation of retinal ganglion cell axon guidance
positive regulation of peptidyl-tyrosine autophosphorylation
positive regulation of p38MAPK cascade
positive regulation of histone deacetylase activity
positive regulation of retinal ganglion cell axon guidance
positive regulation of protein kinase D signaling

Function(s)

fibronectin binding
cytokine activity
platelet-derived growth factor receptor binding
vascular endothelial growth factor receptor binding
protein binding
growth factor activity
heparin binding
chemoattractant activity
identical protein binding
protein homodimerization activity
vascular endothelial growth factor receptor 1 binding
vascular endothelial growth factor receptor 2 binding
protein heterodimerization activity
receptor agonist activity
extracellular matrix binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR06007307.hg.1	TC06000608.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR06007307.hg.1	ENST00000518689.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR06007307.hg.1	ENST00000520948.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR06007307.hg.1	ENST00000523873.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR06007307.hg.1	NM_001025366.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR06007307.hg.1	NM_001025367.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR06007307.hg.1	NM_001171623.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR06007307.hg.1	NM_001171624.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR06007307.hg.1	NM_001171625.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR06007307.hg.1	NM_001204384.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR06007307.hg.1	NM_001204385.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR06007307.hg.1	NM_003376.5	Refseq
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	ENST00000372055.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	ENST00000413642.7	Ensembl
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	ENST00000425836.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	ENST00000480614.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	ENST00000518689.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	ENST00000519767.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	ENST00000520948.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	ENST00000523873.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	ENST00000611736.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	NM_001025366.2	Refseq
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	NM_001025367.2	Refseq
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	NM_001171623.1	Refseq
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	NM_001171624.1	Refseq
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	NM_001171625.1	Refseq
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	NM_001204384.1	Refseq
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	NM_001204385.1	Refseq
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	NM_003376.5	Refseq
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	ENST00000372055.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	ENST00000413642.7	Ensembl
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	ENST00000425836.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	ENST00000480614.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	ENST00000518689.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	ENST00000519767.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	ENST00000520948.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	ENST00000523873.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	ENST00000611736.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	NM_001025366.2	Refseq
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	NM_001025367.2	Refseq
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	NM_001171623.1	Refseq
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	NM_001171624.1	Refseq
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	NM_001171625.1	Refseq
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	NM_001204384.1	Refseq
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	NM_001204385.1	Refseq
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	NM_003376.5	Refseq
Affymetrix Human Clariom D Assay	PSR0600156672.hg.1	TC0600008109.hg.1	Clariom D TC