Hs00912393_g1

• Gene Symbol: KMT2D
• Gene Name: lysine methyltransferase 2D
• Gene Aliases: AAD10, ALR, CAGL114, KABUK1, KMS, MLL2, MLL4, TNRC21
• Chromosome Location: Chr.12: 49018975 - 49060884 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: KMT2D
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_003482.3	NP_003473.3	21 - 22	5185		103
	XM_005269162.4	XP_005269219.1	22 - 23	6464		103
	XM_006719616.3	XP_006719679.1	22 - 23	6461		103
	XM_011538772.2	XP_011537074.1	22 - 23	6467		103
	XM_011538773.2	XP_011537075.1	22 - 23	6464		103
GenBank mRNA	AF010403.1	-	21 - 22	4360		103
	AF010404.1	-	12 - 13	3445		103

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1200012790.hg.1
This assay targets the same location as HTA transcript cluster(s) TC12003277.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Detect Genomic DNA, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene KMT2D

Gene Ontology Categories:

Process(es)

oocyte growth
chromatin silencing
transcription, DNA-templated
regulation of transcription, DNA-templated
positive regulation of cell proliferation
positive regulation of intracellular estrogen receptor signaling pathway
response to estrogen
positive regulation of transcription from RNA polymerase II promoter
oogenesis
histone H3-K4 methylation
beta-catenin-TCF complex assembly

Function(s)

DNA binding
protein binding
zinc ion binding
histone-lysine N-methyltransferase activity
histone methyltransferase activity (H3-K4 specific)
transcription regulatory region DNA binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR12019251.hg.1	TC12003277.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR12019251.hg.1	ENST00000301067.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR12019251.hg.1	NM_003482.3	Refseq
Affymetrix Human Clariom D Assay	PSR1200203145.hg.1	ENST00000301067.11	Ensembl
Affymetrix Human Clariom D Assay	PSR1200203145.hg.1	NM_003482.3	Refseq
Affymetrix Human Clariom D Assay	PSR1200203145.hg.1	ENST00000301067.11	Ensembl
Affymetrix Human Clariom D Assay	PSR1200203145.hg.1	NM_003482.3	Refseq
Affymetrix Human Clariom D Assay	PSR1200203145.hg.1	TC1200012790.hg.1	Clariom D TC