Hs00912411_g1

• Gene Symbol: KMT2D
• Gene Name: lysine methyltransferase 2D
• Gene Aliases: AAD10, ALR, CAGL114, KABUK1, KMS, MLL2, MLL4, TNRC21
• Chromosome Location: Chr.12: 49018975 - 49060884 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: KMT2D
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_003482.3	NP_003473.3	38 - 39	10741		67
	XM_005269162.4	XP_005269219.1	39 - 40	12020		67
	XM_006719614.3	XP_006719677.1	39 - 40	12029		67
	XM_006719616.3	XP_006719679.1	39 - 40	12017		67
	XM_011538770.2	XP_011537072.1	39 - 40	12032		67
	XM_011538771.2	XP_011537073.1	39 - 40	12029		67
	XM_011538772.2	XP_011537074.1	39 - 40	12023		67
	XM_011538773.2	XP_011537075.1	39 - 40	12020		67
	XM_011538774.2	XP_011537076.1	39 - 40	12012		67
	XM_011538776.2	XP_011537078.1	39 - 40	11939		67
GenBank mRNA	AB209494.1	-	5 - 6	2243		67
	AF010403.1	-	38 - 39	9916		67
	AF010404.1	-	29 - 30	9001		67

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1200012790.hg.1
This assay targets the same location as HTA transcript cluster(s) TC12003277.hg.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Detect Genomic DNA, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene KMT2D

Gene Ontology Categories:

Process(es)

oocyte growth
chromatin silencing
transcription, DNA-templated
regulation of transcription, DNA-templated
positive regulation of cell proliferation
positive regulation of intracellular estrogen receptor signaling pathway
response to estrogen
positive regulation of transcription from RNA polymerase II promoter
oogenesis
histone H3-K4 methylation
beta-catenin-TCF complex assembly

Function(s)

DNA binding
protein binding
zinc ion binding
histone-lysine N-methyltransferase activity
histone methyltransferase activity (H3-K4 specific)
transcription regulatory region DNA binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR12019232.hg.1	TC12003277.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR12019232.hg.1	ENST00000301067.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR12019232.hg.1	NM_003482.3	Refseq
Affymetrix Human Clariom D Assay	PSR1200203120.hg.1	ENST00000301067.11	Ensembl
Affymetrix Human Clariom D Assay	PSR1200203120.hg.1	NM_003482.3	Refseq
Affymetrix Human Clariom D Assay	PSR1200203120.hg.1	ENST00000301067.11	Ensembl
Affymetrix Human Clariom D Assay	PSR1200203120.hg.1	NM_003482.3	Refseq
Affymetrix Human Clariom D Assay	PSR1200203120.hg.1	TC1200012790.hg.1	Clariom D TC