Hs00929993_g1

• Gene Symbol: A2M
• Gene Name: alpha-2-macroglobulin
• Gene Aliases: A2MD, CPAMD5, FWP007, S863-7
• Chromosome Location: Chr.12: 9067708 - 9115962 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: A2M
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_000014.4	NP_000005.2	35 - 36	4521		80
GenBank mRNA	AB209614.2	-	35 - 36	4432		80
	AK307832.1	-	34 - 35	4258		80
	BC026246.1	-	17 - 18	2149		80
	BC040071.1	-	35 - 36	4460	6056126	80
	BX647329.1	-	18 - 19	2198		80
	BX648622.1	-		3905		80
	M36501.1	-	16 - 17	1915		80

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1200009847.hg.1
This assay targets the same location as HTA transcript cluster(s) TC12001187.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, 3' Most, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, 1700, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene A2M

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

negative regulation of complement activation, lectin pathway
platelet degranulation
blood coagulation, intrinsic pathway
negative regulation of endopeptidase activity
extracellular matrix disassembly
positive regulation of GTPase activity
stem cell differentiation
regulation of small GTPase mediated signal transduction

Function(s)

protease binding
serine-type endopeptidase inhibitor activity
GTPase activator activity
receptor binding
protein binding
growth factor binding
enzyme binding
interleukin-8 binding
interleukin-1 binding
tumor necrosis factor binding
calcium-dependent protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR12015719.hg.1	ENST00000318602.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR12015719.hg.1	ENST00000540099.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR12015719.hg.1	NM_000014.5	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR12015719.hg.1	TC12001187.hg.1	HTA TC
Affymetrix Human Clariom D Assay	PSR1200174056.hg.1	ENST00000318602.11	Ensembl
Affymetrix Human Clariom D Assay	PSR1200174056.hg.1	ENST00000495442.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1200174056.hg.1	ENST00000495709.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1200174056.hg.1	ENST00000543436.2	Ensembl
Affymetrix Human Clariom D Assay	PSR1200174056.hg.1	NM_000014.5	Refseq
Affymetrix Human Clariom D Assay	PSR1200174056.hg.1	ENST00000318602.11	Ensembl
Affymetrix Human Clariom D Assay	PSR1200174056.hg.1	ENST00000495442.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1200174056.hg.1	ENST00000495709.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1200174056.hg.1	ENST00000543436.2	Ensembl
Affymetrix Human Clariom D Assay	PSR1200174056.hg.1	NM_000014.5	Refseq
Affymetrix Human Clariom D Assay	PSR1200174056.hg.1	TC1200009847.hg.1	Clariom D TC

Array Name	Probe IDs	Targets	Target Type
ABI Human Genome Survey Microarray Version 2.0	167807	-	-