Hs00938193_m1

• Gene Symbol: DLG1
• Gene Name: discs large MAGUK scaffold protein 1
• Gene Aliases: DLGH1, SAP-97, SAP97, dJ1061C18.1.1, hdlg
• Chromosome Location: Chr.3: 197042560 - 197299272 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: DLG1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001098424.1	NP_001091894.1	15 - 16	1831		121
	NM_001204386.1	NP_001191315.1	14 - 15	1732		121
	NM_001204387.1	NP_001191316.1	10 - 11	1616		121
	NM_001204388.1	NP_001191317.1	10 - 11	1616		121
	NM_001290983.1	NP_001277912.1	15 - 16	1900		121
	NM_004087.2	NP_004078.2	15 - 16	1831		121
	XM_005269289.3	XP_005269346.1	15 - 16	2113		121
	XM_011512502.2	XP_011510804.1	15 - 16	2113		121
	XM_011512503.1	XP_011510805.1	14 - 15	2011		121
	XM_011512505.1	XP_011510807.1	14 - 15	2011		121
	XM_011512506.1	XP_011510808.1	13 - 14	1957		121
	XM_011512509.1	XP_011510811.1	14 - 15	2011		121
	XM_017005800.1	XP_016861289.1	15 - 16	2248		121
	XM_017005801.1	XP_016861290.1	15 - 16	1768		121
	XM_017005802.1	XP_016861291.1	15 - 16	1838		121
	XM_017005803.1	XP_016861292.1	15 - 16	1759		121
	XM_017005804.1	XP_016861293.1	15 - 16	2113		121
	XM_017005805.1	XP_016861294.1	15 - 16	1930		121
	XM_017005806.1	XP_016861295.1	14 - 15	2011		121
	XM_017005807.1	XP_016861296.1	14 - 15	2110		121
	XM_017005808.1	XP_016861297.1	14 - 15	1669		121
	XM_017005809.1	XP_016861298.1	14 - 15	1771		121
	XM_017005810.1	XP_016861299.1	14 - 15	1669		121
	XM_017005811.1	XP_016861300.1	13 - 14	1957		121
	XM_017005812.1	XP_016861301.1	13 - 14	1611		121
	XM_017005813.1	XP_016861302.1	13 - 14	1615		121
	XM_017005814.1	XP_016861303.1	13 - 14	1718		121
	XM_017005815.1	XP_016861304.1	13 - 14	1957		121
	XM_017005816.1	XP_016861305.1	14 - 15	2110		121
	XM_017005817.1	XP_016861306.1	14 - 15	1641		121
	XM_017005818.1	XP_016861307.1	14 - 15	1743		121
	XM_017005819.1	XP_016861308.1	14 - 15	1660		121
	XM_017005820.1	XP_016861309.1	13 - 14	1675		121
	XM_017005821.1	XP_016861310.1	11 - 12	4116		121
	XM_017005822.1	XP_016861311.1	11 - 12	4118		121
	XM_017005823.1	XP_016861312.1	10 - 11	4013		121
	XM_017005824.1	XP_016861313.1	5 - 6	632		121
GenBank mRNA	AB209536.2	-	7 - 8	954		121
	AK293967.1	-	10 - 11	1335		121
	AK294772.1	-	10 - 11	1343		121
	AK294855.1	-	10 - 11	1616		121
	AK310596.1	-	14 - 15	1670		121
	AK310893.1	-	15 - 16	2115		121
	BC140841.1	-	15 - 16	1796	9021709	121
	BC144651.1	-	14 - 15	1697	9053182	121
	EF553524.1	-	15 - 16	1900		121
	U13896.1	-	15 - 16	1829		121
	U13897.1	-	15 - 16	1829		121

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0300013736.hg.1
This assay targets the same location as HTA transcript cluster(s) TC03002174.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, 3' Most, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene DLG1

Panther Classification:

Molecular Function -

scaffold/adaptor protein

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
branching involved in ureteric bud morphogenesis
immunological synapse formation
endothelial cell proliferation
lens development in camera-type eye
T cell cytokine production
protein dephosphorylation
actin filament organization
mitotic cell cycle checkpoint
establishment or maintenance of cell polarity
chemical synaptic transmission
nervous system development
positive regulation of cell proliferation
regulation of cell shape
viral process
single organismal cell-cell adhesion
peristalsis
positive regulation of actin filament polymerization
cortical actin cytoskeleton organization
astral microtubule organization
membrane raft organization
regulation of myelination
activation of protein kinase activity
ion transmembrane transport
cellular protein complex localization
T cell activation
negative regulation of T cell proliferation
regulation of membrane potential
amyloid precursor protein metabolic process
receptor clustering
positive regulation of potassium ion transport
cortical microtubule organization
establishment or maintenance of epithelial cell apical/basal polarity
negative regulation of mitotic cell cycle
GMP metabolic process
GDP metabolic process
reproductive structure development
embryonic skeletal system morphogenesis
smooth muscle tissue development
negative regulation of epithelial cell proliferation
establishment of centrosome localization
negative regulation of protein kinase B signaling
hard palate development
negative regulation of ERK1 and ERK2 cascade
bicellular tight junction assembly
protein localization to plasma membrane
positive regulation of establishment of protein localization to plasma membrane
receptor localization to synapse
regulation of NIK/NF-kappaB signaling
regulation of sodium ion transmembrane transport
negative regulation of p38MAPK cascade

Function(s)

guanylate kinase activity
phosphoprotein phosphatase activity
protein binding
protein C-terminus binding
cytoskeletal protein binding
ligand-gated ion channel activity
potassium channel regulator activity
protein kinase binding
phosphatase binding
mitogen-activated protein kinase kinase binding
protein complex scaffold
ionotropic glutamate receptor binding
ion channel binding
L27 domain binding
cadherin binding involved in cell-cell adhesion

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR03038426.hg.1	TC03002174.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR03038426.hg.1	ENST00000314062.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03038426.hg.1	ENST00000346964.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03038426.hg.1	ENST00000357674.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03038426.hg.1	ENST00000359922.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03038426.hg.1	ENST00000381807.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03038426.hg.1	ENST00000392382.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03038426.hg.1	ENST00000419354.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03038426.hg.1	ENST00000422288.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03038426.hg.1	ENST00000443183.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03038426.hg.1	ENST00000448528.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03038426.hg.1	ENST00000450955.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03038426.hg.1	ENST00000452595.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03038426.hg.1	NM_001098424.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR03038426.hg.1	NM_001204386.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR03038426.hg.1	NM_001204387.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR03038426.hg.1	NM_001204388.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR03038426.hg.1	NM_004087.2	Refseq
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000346964.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000357674.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000392381.7	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000392382.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000419227.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000419354.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000422288.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000443183.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000448528.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000450955.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000452595.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000471733.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	NM_001098424.1	Refseq
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	NM_001204386.1	Refseq
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	NM_001204387.1	Refseq
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	NM_001204388.1	Refseq
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	NM_001290983.1	Refseq
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	NM_004087.2	Refseq
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000346964.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000357674.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000392381.7	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000392382.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000419227.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000419354.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000422288.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000443183.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000448528.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000450955.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000452595.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	ENST00000471733.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	NM_001098424.1	Refseq
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	NM_001204386.1	Refseq
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	NM_001204387.1	Refseq
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	NM_001204388.1	Refseq
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	NM_001290983.1	Refseq
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	NM_004087.2	Refseq
Affymetrix Human Clariom D Assay	PSR0300202690.hg.1	TC0300013736.hg.1	Clariom D TC