Hs00938325_m1

• Gene Symbol: PDE4D
• Gene Name: phosphodiesterase 4D
• Gene Aliases: ACRDYS2, DPDE3, HSPDE4D, PDE43, PDE4DN2, STRK1
• Chromosome Location: Chr.5: 58969038 - 60488098 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: PDE4D
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001104631.1	NP_001098101.1	6 - 7	1086		62
	NM_001165899.1	NP_001159371.1	8 - 9	977		62
	NM_001197218.1	NP_001184147.1	6 - 7	825		62
	NM_001197219.1	NP_001184148.1	6 - 7	603		62
	NM_001197220.1	NP_001184149.1	6 - 7	1241		62
	NM_001197221.1	NP_001184150.1	2 - 3	561		62
	NM_001197222.1	NP_001184151.1	1 - 2	647		62
	NM_006203.4	NP_006194.2	6 - 7	629		62
	XM_005248537.3	XP_005248594.1	6 - 7	1783		62
	XM_005248538.4	XP_005248595.1	7 - 8	3684		62
	XM_011543469.1	XP_011541771.1	9 - 10	1066		62
	XM_011543470.2	XP_011541772.1	9 - 10	990		62
	XM_011543471.1	XP_011541773.1	8 - 9	943		62
	XM_011543473.1	XP_011541775.1	8 - 9	891		62
	XM_011543477.2	XP_011541779.1	8 - 9	893		62
	XM_017009565.1	XP_016865054.1	9 - 10	1103		62
	XM_017009566.1	XP_016865055.1	9 - 10	993		62
	XM_017009567.1	XP_016865056.1	7 - 8	731		62
	XM_017009568.1	XP_016865057.1	9 - 10	977		62
	XM_017009569.1	XP_016865058.1	8 - 9	856		62
	XM_017009570.1	XP_016865059.1	5 - 6	1676		62
	XM_017009571.1	XP_016865060.1	8 - 9	899		62
GenBank mRNA	AF012073.1	-	6 - 7	839		62
	AF012074.1	-	2 - 3	575		62
	AF536976.1	-	8 - 9	800		62
	AF536977.1	-	6 - 7	603		62
	AJ250852.1	-	2 - 3	171		62
	AJ250854.1	-	7 - 8	766		62
	AY245866.1	-	8 - 9	942		62
	AY245867.1	-	6 - 7	1241		62
	AY388960.1	-	6 - 7	524		62
	L20970.1	-	6 - 7	637		62
	U02882.1	-	5 - 6	407		62
	U50157.1	-	1 - 2	245		62
	U50158.1	-	2 - 3	159		62
	U50159.1	-	6 - 7	580		62
	U79571.1	-	1 - 2	650		62

More Information

Additional Information:

This assay is in the 5'UTR region of the AF012074.1, NM_001197221.1, U50158.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene PDE4D

Panther Classification:

Molecular Function -

phosphodiesterase

Gene Ontology Categories:

Process(es)

regulation of heart rate
cAMP catabolic process
smooth muscle contraction
aging
regulation of receptor activity
regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
cAMP-mediated signaling
neutrophil chemotaxis
regulation of cAMP metabolic process
positive regulation of interferon-gamma production
positive regulation of interleukin-2 production
positive regulation of interleukin-5 production
negative regulation of peptidyl-serine phosphorylation
multicellular organism growth
negative regulation of heart contraction
T cell receptor signaling pathway
regulation of ryanodine-sensitive calcium-release channel activity
establishment of endothelial barrier
cellular response to lipopolysaccharide
cellular response to epinephrine stimulus
adrenergic receptor signaling pathway
regulation of cardiac muscle cell contraction
adrenergic receptor signaling pathway involved in positive regulation of heart rate
regulation of cell communication by electrical coupling involved in cardiac conduction
negative regulation of relaxation of cardiac muscle

Function(s)

3',5'-cyclic-nucleotide phosphodiesterase activity
3',5'-cyclic-AMP phosphodiesterase activity
protein binding
drug binding
enzyme binding
cAMP binding
beta-2 adrenergic receptor binding
ion channel binding
metal ion binding
ATPase binding
scaffold protein binding