Hs00938685_m1

• Gene Symbol: MAP2K5
• Gene Name: mitogen-activated protein kinase kinase 5
• Gene Aliases: HsT17454, MAPKK5, MEK5, PRKMK5
• Chromosome Location: Chr.15: 67542606 - 67807117 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: MAP2K5
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_002757.3	NP_002748.1	16 - 17	1703		75
GenBank mRNA	U71088.2	-	16 - 17	1055		75

More Information

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene MAP2K5

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
activation of MAPK activity
signal transduction
heart development
peptidyl-tyrosine phosphorylation
positive regulation of cell growth
negative regulation of NF-kappaB transcription factor activity
negative regulation of heterotypic cell-cell adhesion
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of interleukin-8 biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
positive regulation of epithelial cell proliferation
positive regulation of protein metabolic process
negative regulation of response to cytokine stimulus
ERK5 cascade
cellular response to growth factor stimulus
cellular response to laminar fluid shear stress
negative regulation of cell migration involved in sprouting angiogenesis
negative regulation of chemokine (C-X-C motif) ligand 2 production
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

protein kinase activity
receptor signaling protein serine/threonine kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
metal ion binding