Hs00938687_m1

• Gene Symbol: MAP2K5
• Gene Name: mitogen-activated protein kinase kinase 5
• Gene Aliases: HsT17454, MAPKK5, MEK5, PRKMK5
• Chromosome Location: Chr.15: 67542606 - 67807117 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: MAP2K5
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001206804.1	NP_001193733.1	19 - 20	1205		62
	NM_002757.3	NP_002748.1	18 - 19	1759		62
	NM_145160.2	NP_660143.1	19 - 20	1789		62
GenBank mRNA	AK024766.1	-	8 - 9	383		62
	AK057521.1	-	13 - 14	917		62
	AK293459.1	-	19 - 20	1205		62
	AK315435.1	-	19 - 20	1336		62
	BC008838.2	-	19 - 20	1446	4100679	62
	BT006780.1	-	19 - 20	1136		62
	CR542229.1	-	19 - 20	1136		62
	U71087.1	-	19 - 20	1197		62
	U71088.2	-	18 - 19	1111		62

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1500007645.hg.1
This assay targets the same location as HTA transcript cluster(s) TC15000625.hg.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene MAP2K5

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
activation of MAPK activity
signal transduction
heart development
peptidyl-tyrosine phosphorylation
positive regulation of cell growth
negative regulation of NF-kappaB transcription factor activity
negative regulation of heterotypic cell-cell adhesion
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
negative regulation of interleukin-8 biosynthetic process
positive regulation of transcription from RNA polymerase II promoter
positive regulation of epithelial cell proliferation
positive regulation of protein metabolic process
negative regulation of response to cytokine stimulus
ERK5 cascade
cellular response to growth factor stimulus
cellular response to laminar fluid shear stress
negative regulation of cell migration involved in sprouting angiogenesis
negative regulation of chemokine (C-X-C motif) ligand 2 production
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Function(s)

protein kinase activity
receptor signaling protein serine/threonine kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
metal ion binding