Hs00945144_m1

• Gene Symbol: TEK
• Gene Name: TEK receptor tyrosine kinase
• Gene Aliases: CD202B, TIE-2, TIE2, VMCM, VMCM1
• Chromosome Location: Chr.9: 27109141 - 27230178 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: TEK
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_000459.4	NP_000450.2	20 - 21	3556		92
	NM_001290077.1	NP_001277006.1	19 - 20	3427		92
	NM_001290078.1	NP_001277007.1	18 - 19	3112		92
	XM_005251561.1	XP_005251618.1	20 - 21	3220		92
	XM_005251563.1	XP_005251620.1	19 - 20	3091		92
GenBank mRNA	AB208796.1	-	20 - 21	3234		92
	AK291775.1	-	20 - 21	3244		92
	AK294887.1	-	18 - 19	3113		92
	AK295043.1	-	19 - 20	3153		92
	BC035514.1	-	20 - 21	3231	5228999	92
	L06139.1	-	20 - 21	3254		92

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0900006886.hg.1
This assay targets the same location as HTA transcript cluster(s) TC09000121.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Protein Kinase, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene TEK

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
angiogenesis
response to hypoxia
positive regulation of protein phosphorylation
endothelial cell proliferation
positive regulation of endothelial cell proliferation
endochondral ossification
sprouting angiogenesis
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
cell-cell signaling
heart development
positive regulation of endothelial cell migration
positive regulation of phosphatidylinositol 3-kinase signaling
negative regulation of angiogenesis
peptidyl-tyrosine phosphorylation
organ regeneration
regulation of establishment or maintenance of cell polarity
substrate adhesion-dependent cell spreading
negative regulation of apoptotic process
regulation of vascular permeability
response to peptide hormone
positive regulation of GTPase activity
positive regulation of phosphatidylinositol 3-kinase activity
response to estrogen
positive regulation of angiogenesis
protein autophosphorylation
Tie signaling pathway
negative regulation of inflammatory response
leukocyte migration
protein oligomerization
response to cAMP
positive regulation of focal adhesion assembly
positive regulation of protein kinase B signaling
definitive hemopoiesis
heart trabecula formation
positive regulation of ERK1 and ERK2 cascade
positive regulation of intracellular signal transduction
positive regulation of actin cytoskeleton reorganization
regulation of endothelial cell apoptotic process
negative regulation of endothelial cell apoptotic process

Function(s)

protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
ATP binding
growth factor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR09001424.hg.1	TC09000121.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR09001424.hg.1	ENST00000380036.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR09001424.hg.1	ENST00000406359.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR09001424.hg.1	ENST00000519097.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR09001424.hg.1	NM_000459.4	Refseq
Affymetrix Human Clariom D Assay	PSR0900146870.hg.1	ENST00000380036.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0900146870.hg.1	ENST00000406359.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0900146870.hg.1	ENST00000519097.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0900146870.hg.1	ENST00000615002.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0900146870.hg.1	NM_000459.4	Refseq
Affymetrix Human Clariom D Assay	PSR0900146870.hg.1	NM_001290077.1	Refseq
Affymetrix Human Clariom D Assay	PSR0900146870.hg.1	NM_001290078.1	Refseq
Affymetrix Human Clariom D Assay	PSR0900146870.hg.1	ENST00000380036.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0900146870.hg.1	ENST00000406359.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0900146870.hg.1	ENST00000519097.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0900146870.hg.1	ENST00000615002.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0900146870.hg.1	NM_000459.4	Refseq
Affymetrix Human Clariom D Assay	PSR0900146870.hg.1	NM_001290077.1	Refseq
Affymetrix Human Clariom D Assay	PSR0900146870.hg.1	NM_001290078.1	Refseq
Affymetrix Human Clariom D Assay	PSR0900146870.hg.1	TC0900006886.hg.1	Clariom D TC