Hs00954130_m1

• Gene Symbol: PPM1B
• Gene Name: protein phosphatase, Mg2+/Mn2+ dependent 1B
• Gene Aliases: PP2C-beta, PP2C-beta-X, PP2CB, PP2CBETA, PPC2BETAX
• Chromosome Location: Chr.2: 44168803 - 44247330 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: PPM1B
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_177969.3	NP_808908.1	1 - 2	472		90
GenBank mRNA	BC012002.1	-	1 - 2	374		90

More Information

Updated Mapping Information

This assay targets the same location as HTA transcript cluster(s) TC02000274.hg.1

Additional Information:

This assay is in the 5'UTR region of the BC012002.1,NM_177969.3 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Protein Phosphatase, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene PPM1B

Gene Ontology Categories:

Process(es)

protein dephosphorylation
N-terminal protein myristoylation
negative regulation of interferon-beta production
peptidyl-threonine dephosphorylation
negative regulation of NF-kappaB import into nucleus
negative regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of defense response to virus

Function(s)

magnesium ion binding
protein serine/threonine phosphatase activity
protein binding
manganese ion binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR02004084.hg.1	TC02000274.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR02004084.hg.1	ENST00000282412.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02004084.hg.1	ENST00000345249.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02004084.hg.1	ENST00000378540.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02004084.hg.1	ENST00000378551.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02004084.hg.1	ENST00000409432.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02004084.hg.1	ENST00000409895.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02004084.hg.1	NM_001033557.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR02004084.hg.1	NM_002706.5	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR02004084.hg.1	NM_177968.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR02004084.hg.1	NM_177969.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR02004085.hg.1	TC02000274.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR02004085.hg.1	ENST00000282412.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02004085.hg.1	ENST00000345249.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02004085.hg.1	ENST00000378540.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02004085.hg.1	ENST00000378551.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02004085.hg.1	ENST00000409432.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02004085.hg.1	ENST00000409895.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02004085.hg.1	NM_001033557.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR02004085.hg.1	NM_002706.5	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR02004085.hg.1	NM_177968.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR02004085.hg.1	NM_177969.3	Refseq