Hs00955521_m1

• Gene Symbol: ERBB4
• Gene Name: erb-b2 receptor tyrosine kinase 4
• Gene Aliases: ALS19, HER4, p180erbB4
• Chromosome Location: Chr.2: 211375717 - 212539147 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: ERBB4
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_005235.2	NP_005226.1	26 - 27	3282		70
	XM_005246376.2	XP_005246433.1	26 - 27	3771		70
	XM_006712364.2	XP_006712427.1	27 - 28	3846		70
	XM_017003577.1	XP_016859066.1	28 - 29	3924		70
	XM_017003578.1	XP_016859067.1	27 - 28	3879		70
	XM_017003580.1	XP_016859069.1	27 - 28	3849		70
	XM_017003582.1	XP_016859071.1	23 - 24	2959		70
GenBank mRNA	BC112199.1	-	26 - 27	3223	8327667	70
	BC143747.1	-	26 - 27	3181	9052261	70
	L07868.1	-	26 - 27	3217		70

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0200015616.hg.1
This assay targets the same location as HTA transcript cluster(s) TC02002735.hg.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Apoptosis, Protein Kinase, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene ERBB4

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
neural crest cell migration
positive regulation of protein phosphorylation
transcription, DNA-templated
signal transduction
transmembrane receptor protein tyrosine kinase signaling pathway
nervous system development
heart development
lactation
cell proliferation
positive regulation of cell proliferation
negative regulation of cell proliferation
embryonic pattern specification
regulation of phosphatidylinositol 3-kinase signaling
positive regulation of phosphatidylinositol 3-kinase signaling
cell migration
peptidyl-tyrosine phosphorylation
central nervous system morphogenesis
olfactory bulb interneuron differentiation
regulation of cell migration
ERBB2 signaling pathway
positive regulation of tyrosine phosphorylation of Stat5 protein
positive regulation of GTPase activity
mitochondrial fragmentation involved in apoptotic process
cell fate commitment
positive regulation of transcription, DNA-templated
protein autophosphorylation
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
positive regulation of cardiac muscle cell proliferation
mammary gland epithelial cell differentiation
mammary gland alveolus development
cardiac muscle tissue regeneration
positive regulation of ERK1 and ERK2 cascade
positive regulation of protein localization to cell surface
regulation of cell motility
positive regulation of STAT protein import into nucleus
negative regulation of neuron migration

Function(s)

protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
receptor signaling protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
epidermal growth factor receptor binding
protein binding
ATP binding
protein homodimerization activity
transcription regulatory region DNA binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR02043912.hg.1	TC02002735.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR02043912.hg.1	ENST00000342788.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02043912.hg.1	ENST00000402597.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02043912.hg.1	ENST00000436443.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR02043912.hg.1	NM_001042599.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR02043912.hg.1	NM_005235.2	Refseq
Affymetrix Human Clariom D Assay	PSR0200214536.hg.1	ENST00000342788.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214536.hg.1	ENST00000402597.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214536.hg.1	ENST00000436443.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214536.hg.1	NM_001042599.1	Refseq
Affymetrix Human Clariom D Assay	PSR0200214536.hg.1	NM_005235.2	Refseq
Affymetrix Human Clariom D Assay	PSR0200214536.hg.1	ENST00000342788.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214536.hg.1	ENST00000402597.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214536.hg.1	ENST00000436443.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0200214536.hg.1	NM_001042599.1	Refseq
Affymetrix Human Clariom D Assay	PSR0200214536.hg.1	NM_005235.2	Refseq
Affymetrix Human Clariom D Assay	PSR0200214536.hg.1	TC0200015616.hg.1	Clariom D TC