Hs00966521_m1

• Gene Symbol: PDGFB
• Gene Name: platelet derived growth factor subunit B
• Gene Aliases: IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis
• Chromosome Location: Chr.22: 39223359 - 39245055 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: PDGFB
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_002608.3	NP_002599.1	2 - 3	1253		83
	NM_033016.3	NP_148937.1	2 - 3	153		83
GenBank mRNA	BC029822.1	-	2 - 3	473	5174750	83
	BC077725.1	-	2 - 3	985	6379783	83
	CR456538.1	-	2 - 3	169		83
	CR541807.1	-	2 - 3	161		83
	M12783.1	-	2 - 3	1253		83
	X02744.1	-	2 - 3	278		83
	X02811.1	-	2 - 3	1143		83
	X03702.1	-	1 - 2	86		83
	X83705.1	-	2 - 3	153		83

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC2200008741.hg.1
This assay targets the same location as HTA transcript cluster(s) TC22000802.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene PDGFB

Panther Classification:

Molecular Function -

growth factor

Gene Ontology Categories:

Process(es)

MAPK cascade
response to hypoxia
embryonic placenta development
positive regulation of endothelial cell proliferation
monocyte chemotaxis
platelet degranulation
positive regulation of glomerular filtration
DNA replication
protein phosphorylation
transforming growth factor beta receptor signaling pathway
heart development
positive regulation of cell proliferation
response to wounding
negative regulation of phosphatidylinositol biosynthetic process
negative regulation of platelet activation
positive regulation of gene expression
negative regulation of gene expression
regulation of phosphatidylinositol 3-kinase signaling
positive regulation of phosphatidylinositol 3-kinase signaling
positive regulation of smooth muscle cell migration
cell growth
peptidyl-serine phosphorylation
peptidyl-tyrosine phosphorylation
hemopoiesis
extracellular matrix organization
positive regulation of cell migration
positive regulation of protein autophosphorylation
negative regulation of protein binding
activation of protein kinase activity
activation of protein kinase B activity
response to estradiol
response to insulin
positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway
paracrine signaling
wound healing
response to drug
positive regulation of MAP kinase activity
positive regulation of MAPK cascade
positive regulation of blood vessel endothelial cell migration
positive regulation of GTPase activity
positive regulation of phosphatidylinositol 3-kinase activity
response to estrogen
positive regulation of cyclin-dependent protein serine/threonine kinase activity
positive regulation of DNA replication
positive regulation of mitotic nuclear division
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
phosphatidylinositol phosphorylation
platelet-derived growth factor receptor signaling pathway
phosphatidylinositol-mediated signaling
positive regulation of fibroblast proliferation
positive regulation of smooth muscle cell proliferation
positive regulation of peptidyl-tyrosine phosphorylation
positive chemotaxis
positive regulation of chemotaxis
positive regulation of cell division
cell chemotaxis
positive regulation of protein tyrosine kinase activity
positive regulation of ERK1 and ERK2 cascade
protein kinase C signaling
cellular response to growth factor stimulus
cellular response to mycophenolic acid
positive regulation of glomerular mesangial cell proliferation
metanephric glomerular mesangial cell development
reactive oxygen species metabolic process
positive regulation of calcium ion import
positive regulation of hyaluronan biosynthetic process
negative regulation of pri-miRNA transcription from RNA polymerase II promoter
positive regulation of pri-miRNA transcription from RNA polymerase II promoter
positive regulation of vascular smooth muscle cell proliferation
positive regulation of vascular associated smooth muscle cell migration
negative regulation of vascular smooth muscle cell differentiation
positive regulation of vascular smooth muscle cell dedifferentiation
positive regulation of reactive oxygen species metabolic process
positive regulation of DNA biosynthetic process
positive regulation of metanephric mesenchymal cell migration

Function(s)

Ras guanyl-nucleotide exchange factor activity
platelet-derived growth factor receptor binding
protein binding
collagen binding
growth factor activity
superoxide-generating NADPH oxidase activator activity
chemoattractant activity
identical protein binding
protein homodimerization activity
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
protein heterodimerization activity
platelet-derived growth factor binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000440375.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000440375.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000440375.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000440375.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000440375.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000455790.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000455790.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000455790.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000455790.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000455790.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	ENST00000455790.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR22013618.hg.1	ENST00000331163.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR22013618.hg.1	ENST00000381551.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR22013618.hg.1	NM_002608.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR22013618.hg.1	NM_033016.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR22013618.hg.1	TC22000802.hg.1	HTA TC
Affymetrix Human Clariom D Assay	PSR2200163390.hg.1	TC2200008741.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	PSR2200163390.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Clariom D Assay	PSR2200163390.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Clariom D Assay	PSR2200163390.hg.1	ENST00000440375.1	Ensembl
Affymetrix Human Clariom D Assay	PSR2200163390.hg.1	ENST00000455790.5	Ensembl
Affymetrix Human Clariom D Assay	PSR2200163390.hg.1	NM_002608.3	Refseq
Affymetrix Human Clariom D Assay	PSR2200163390.hg.1	NM_033016.3	Refseq
Affymetrix Human Clariom D Assay	PSR2200163390.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Clariom D Assay	PSR2200163390.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Clariom D Assay	PSR2200163390.hg.1	ENST00000440375.1	Ensembl
Affymetrix Human Clariom D Assay	PSR2200163390.hg.1	ENST00000455790.5	Ensembl
Affymetrix Human Clariom D Assay	PSR2200163390.hg.1	NM_002608.3	Refseq
Affymetrix Human Clariom D Assay	PSR2200163390.hg.1	NM_033016.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000331163.10	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000381551.8	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000440375.1	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000440375.1	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000440375.1	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000440375.1	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000440375.1	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000455790.5	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000455790.5	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000455790.5	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000455790.5	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000455790.5	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	ENST00000455790.5	Ensembl
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_002608.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_033016.3	Refseq
Affymetrix Human Clariom D Assay	TC2200008741.hg.1	NM_033016.3	Refseq