Hs00976050_m1

• Gene Symbol: ITPR1
• Gene Name: inositol 1,4,5-trisphosphate receptor type 1
• Gene Aliases: ACV, CLA4, INSP3R1, IP3R, IP3R1, PPP1R94, SCA15, SCA16, SCA29
• Chromosome Location: Chr.3: 4493348 - 4847840 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: ITPR1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001099952.2	NP_001093422.2	46 - 47	6595		94
	NM_001168272.1	NP_001161744.1	48 - 49	6694		94
	NM_002222.5	NP_002213.5	45 - 46	6550		94
	XM_005265109.2	XP_005265166.1	47 - 48	6670		94
	XM_005265110.2	XP_005265167.1	46 - 47	6622		94
	XM_006713131.2	XP_006713194.1	47 - 48	6673		94
	XM_011533681.1	XP_011531983.1	49 - 50	6742		94
	XM_011533682.2	XP_011531984.1	49 - 50	6668		94
	XM_011533683.2	XP_011531985.1	49 - 50	6739		94
	XM_011533684.1	XP_011531986.1	49 - 50	6715		94
	XM_011533685.1	XP_011531987.1	48 - 49	6709		94
	XM_011533686.1	XP_011531988.1	48 - 49	6706		94
	XM_011533687.1	XP_011531989.1	48 - 49	6697		94
	XM_011533688.1	XP_011531990.1	48 - 49	6670		94
	XM_011533690.1	XP_011531992.1	49 - 50	6742		94
	XM_017006357.1	XP_016861846.1	49 - 50	6739		94
GenBank mRNA	AB208868.1	-	26 - 27	3466		94
	D26070.1	-	45 - 46	6456		94
	L38019.2	-	46 - 47	6492		94
	U23850.1	-	46 - 47	6344		94

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0300006477.hg.1
This assay targets the same location as HTA transcript cluster(s) TC03000013.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 86 and 100, Ion Channel, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene ITPR1

Panther Classification:

Molecular Function -

ligand-gated ion channel

Gene Ontology Categories:

Process(es)

response to hypoxia
calcium ion transport
signal transduction
post-embryonic development
regulation of autophagy
platelet activation
endoplasmic reticulum calcium ion homeostasis
epithelial fluid transport
inositol phosphate-mediated signaling
regulation of insulin secretion
negative regulation of calcium-mediated signaling
voluntary musculoskeletal movement
release of sequestered calcium ion into cytosol
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
regulation of cardiac conduction

Function(s)

inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
protein binding
calcium ion transmembrane transporter activity
calcium-release channel activity
calcium channel inhibitor activity
phosphatidylinositol binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR03000328.hg.1	TC03000013.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR03000328.hg.1	ENST00000302640.8	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03000328.hg.1	ENST00000354582.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03000328.hg.1	ENST00000356617.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03000328.hg.1	ENST00000357086.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03000328.hg.1	ENST00000423119.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03000328.hg.1	ENST00000426160.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03000328.hg.1	ENST00000443694.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03000328.hg.1	ENST00000456211.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03000328.hg.1	NM_001099952.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR03000328.hg.1	NM_001168272.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR03000328.hg.1	NM_002222.5	Refseq
Affymetrix Human Clariom D Assay	PSR0300144486.hg.1	ENST00000302640.12	Ensembl
Affymetrix Human Clariom D Assay	PSR0300144486.hg.1	ENST00000354582.10	Ensembl
Affymetrix Human Clariom D Assay	PSR0300144486.hg.1	ENST00000357086.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0300144486.hg.1	ENST00000443694.2	Ensembl
Affymetrix Human Clariom D Assay	PSR0300144486.hg.1	ENST00000456211.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0300144486.hg.1	ENST00000481415.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0300144486.hg.1	NM_001099952.2	Refseq
Affymetrix Human Clariom D Assay	PSR0300144486.hg.1	NM_001168272.1	Refseq
Affymetrix Human Clariom D Assay	PSR0300144486.hg.1	NM_002222.5	Refseq
Affymetrix Human Clariom D Assay	PSR0300144486.hg.1	ENST00000302640.12	Ensembl
Affymetrix Human Clariom D Assay	PSR0300144486.hg.1	ENST00000354582.10	Ensembl
Affymetrix Human Clariom D Assay	PSR0300144486.hg.1	ENST00000357086.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0300144486.hg.1	ENST00000443694.2	Ensembl
Affymetrix Human Clariom D Assay	PSR0300144486.hg.1	ENST00000456211.6	Ensembl
Affymetrix Human Clariom D Assay	PSR0300144486.hg.1	ENST00000481415.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0300144486.hg.1	NM_001099952.2	Refseq
Affymetrix Human Clariom D Assay	PSR0300144486.hg.1	NM_001168272.1	Refseq
Affymetrix Human Clariom D Assay	PSR0300144486.hg.1	NM_002222.5	Refseq
Affymetrix Human Clariom D Assay	PSR0300144486.hg.1	TC0300006477.hg.1	Clariom D TC