Hs00978072_m1 Best Coverage

• Gene Symbol: GCLM
• Gene Name: glutamate-cysteine ligase modifier subunit
• Gene Aliases: GLCLR
• Chromosome Location: Chr.1: 93885199 - 93909598 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: GCLM
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001308253.1	NP_001295182.1	4 - 5	903		102
	NM_002061.3	NP_002052.1	5 - 6	969		102
	XM_011541261.2	XP_011539563.1	5 - 6	770		102
	XM_017001056.1	XP_016856545.1	5 - 6	969		102
	XM_017001057.1	XP_016856546.1	4 - 5	903		102
GenBank mRNA	AB809606.1	-	4 - 5	558		102
	AK290449.1	-	5 - 6	968		102
	BC041809.1	-	5 - 6	770	5311598	102
	CR541833.1	-	5 - 6	534		102
	L35546.1	-	5 - 6	787		102

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0100014966.hg.1
This assay targets the same location as HTA transcript cluster(s) TC01002882.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Recommended Assay, Homo sapiens, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene GCLM

Panther Classification:

Molecular Function -

ligase, metabolite interconversion enzyme

Gene Ontology Categories:

Process(es)

sulfur amino acid metabolic process
cysteine metabolic process
glutamate metabolic process
glutathione biosynthetic process
response to oxidative stress
apoptotic mitochondrial changes
positive regulation of glutamate-cysteine ligase activity
response to drug
negative regulation of neuron apoptotic process
regulation of blood vessel size
response to nitrosative stress
regulation of mitochondrial depolarization
negative regulation of extrinsic apoptotic signaling pathway

Function(s)

glutamate-cysteine ligase activity
enzyme regulator activity
glutamate-cysteine ligase catalytic subunit binding
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR01044951.hg.1	TC01002882.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR01044951.hg.1	ENST00000370238.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR01044951.hg.1	NM_002061.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR01044952.hg.1	TC01002882.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR01044952.hg.1	ENST00000370238.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR01044952.hg.1	NM_002061.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR01044953.hg.1	TC01002882.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR01044953.hg.1	ENST00000370238.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR01044953.hg.1	ENST00000467772.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR01044953.hg.1	NM_002061.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000462183.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000462183.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000462183.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000462183.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000467772.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000467772.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000467772.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000467772.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000467772.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000467772.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000462183.1	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000462183.1	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000462183.1	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000462183.1	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000467772.1	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000467772.1	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000467772.1	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000467772.1	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000467772.1	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000467772.1	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_001308253.1	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Clariom D Assay	TC0100014966.hg.1	NM_002061.3	Refseq
Affymetrix Human Clariom D Assay	PSR0100211521.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Clariom D Assay	PSR0100211521.hg.1	ENST00000467772.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0100211521.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0100211521.hg.1	NM_001308253.1	Refseq
Affymetrix Human Clariom D Assay	PSR0100211521.hg.1	NM_002061.3	Refseq
Affymetrix Human Clariom D Assay	PSR0100211521.hg.1	ENST00000370238.7	Ensembl
Affymetrix Human Clariom D Assay	PSR0100211521.hg.1	ENST00000467772.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0100211521.hg.1	ENST00000615724.1	Ensembl
Affymetrix Human Clariom D Assay	PSR0100211521.hg.1	NM_001308253.1	Refseq
Affymetrix Human Clariom D Assay	PSR0100211521.hg.1	NM_002061.3	Refseq
Affymetrix Human Clariom D Assay	PSR0100211521.hg.1	TC0100014966.hg.1	Clariom D TC