Hs00985383_m1

• Gene Symbol: ITGA2
• Gene Name: integrin subunit alpha 2
• Gene Aliases: BR, CD49B, GPIa, HPA-5, VLA-2, VLAA2
• Chromosome Location: Chr.5: 52989326 - 53094779 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: ITGA2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_002203.3	NP_002194.2	2 - 3	329		62
	NR_073103.1		2 - 3	329		62
	NR_073104.1		2 - 3	329		62
	NR_073105.1		2 - 3	329		62
	NR_073106.1		2 - 3	329		62
GenBank mRNA	AK307952.1	-	2 - 3	318		62
	BC143505.1	-	2 - 3	215		62
	BC143508.1	-	2 - 3	215		62
	BC143509.1	-	2 - 3	215		62
	BC143511.1	-	2 - 3	215		62
	BP280760.1	-	2 - 3	331		62
	X17033.1	-	2 - 3	234		62

More Information

Updated Mapping Information

This assay targets the same location as HTA transcript cluster(s) TC05000218.hg.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene ITGA2

Panther Classification:

Molecular Function -

integrin

Gene Ontology Categories:

Process(es)

response to hypoxia
positive regulation of leukocyte migration
substrate-dependent cell migration
hypotonic response
cell adhesion
cell-matrix adhesion
integrin-mediated signaling pathway
female pregnancy
blood coagulation
cell proliferation
organ morphogenesis
positive regulation of epithelial cell migration
positive regulation of alkaline phosphatase activity
response to amine
response to muscle activity
positive regulation of smooth muscle cell migration
extracellular matrix organization
mammary gland development
positive regulation of cell projection organization
cell-substrate adhesion
positive regulation of collagen biosynthetic process
positive regulation of collagen binding
response to L-ascorbic acid
cell adhesion mediated by integrin
collagen-activated signaling pathway
response to drug
positive regulation of DNA binding
skin morphogenesis
establishment of protein localization
positive regulation of translation
positive regulation of cell adhesion
positive regulation of smooth muscle contraction
viral entry into host cell
focal adhesion assembly
mesodermal cell differentiation
positive regulation of smooth muscle cell proliferation
positive regulation of inflammatory response
positive regulation of positive chemotaxis
detection of mechanical stimulus involved in sensory perception of pain
positive regulation of transmission of nerve impulse
positive regulation of phagocytosis, engulfment
hepatocyte differentiation
response to parathyroid hormone
cellular response to mechanical stimulus
cellular response to estradiol stimulus

Function(s)

virus receptor activity
integrin binding
protein binding
collagen binding
protein complex binding
collagen receptor activity
laminin binding
metal ion binding
protein heterodimerization activity
collagen binding involved in cell-matrix adhesion

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR05002677.hg.1	TC05000218.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR05002677.hg.1	ENST00000296585.5	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05002677.hg.1	NM_002203.3	Refseq