Hs00990010_m1

• Gene Symbol: RAD50
• Gene Name: RAD50 double strand break repair protein
• Gene Aliases: NBSLD, RAD502, hRad50
• Chromosome Location: Chr.5: 132556924 - 132644621 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: RAD50
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_005732.3	NP_005723.2	11 - 12	2191		149
GenBank mRNA	AF057299.1	-	11 - 12	2111		149
	AF057300.1	-	11 - 12	2046		149
	AK307439.1	-	11 - 12	1866		149
	BC073850.1	-	11 - 12	2108		149
	BC108282.1	-	11 - 12	2128		149
	BC136436.1	-	11 - 12	2083	9020425	149
	U63139.1	-	11 - 12	2178		149

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0500008641.hg.1
This assay targets the same location as HTA transcript cluster(s) TC05000639.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene RAD50

Gene Ontology Categories:

Process(es)

regulation of mitotic recombination
telomere maintenance via recombination
telomere maintenance
double-strand break repair via homologous recombination
DNA double-strand break processing
DNA synthesis involved in DNA repair
strand displacement
DNA replication
DNA repair
double-strand break repair
double-strand break repair via nonhomologous end joining
DNA recombination
cellular response to DNA damage stimulus
telomere maintenance via telomerase
reciprocal meiotic recombination
viral process
telomeric 3' overhang formation
positive regulation of protein autophosphorylation
positive regulation of telomere maintenance
DNA duplex unwinding
positive regulation of kinase activity
nucleotide phosphorylation
chromosome organization involved in meiotic cell cycle
nucleic acid phosphodiester bond hydrolysis
regulation of signal transduction by p53 class mediator
negative regulation of telomere capping

Function(s)

single-stranded DNA endodeoxyribonuclease activity
DNA binding
DNA helicase activity
double-stranded telomeric DNA binding
adenylate kinase activity
protein binding
ATP binding
3'-5' exonuclease activity
protein-macromolecule adaptor activity
single-stranded telomeric DNA binding
metal ion binding
G-quadruplex DNA binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR05008840.hg.1	ENST00000265335.6	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05008840.hg.1	ENST00000378823.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05008840.hg.1	NM_005732.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR05008840.hg.1	TC05000639.hg.1	HTA TC
Affymetrix Human Clariom D Assay	PSR0500159259.hg.1	ENST00000378823.7	Ensembl
Affymetrix Human Clariom D Assay	PSR0500159259.hg.1	ENST00000423956.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0500159259.hg.1	ENST00000453394.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0500159259.hg.1	ENST00000533482.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0500159259.hg.1	NM_005732.3	Refseq
Affymetrix Human Clariom D Assay	PSR0500159259.hg.1	TC0500008641.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	PSR0500159259.hg.1	ENST00000533482.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0500159259.hg.1	ENST00000378823.7	Ensembl
Affymetrix Human Clariom D Assay	PSR0500159259.hg.1	ENST00000423956.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0500159259.hg.1	ENST00000453394.5	Ensembl
Affymetrix Human Clariom D Assay	PSR0500159259.hg.1	NM_005732.3	Refseq