Hs00992114_m1

• Gene Symbol: ATR
• Gene Name: ATR serine/threonine kinase
• Gene Aliases: FCTCS, FRP1, MEC1, SCKL, SCKL1
• Chromosome Location: Chr.3: 142449235 - 142578826 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: ATR
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001184.3	NP_001175.2	20 - 21	3941		144
	XM_011512924.1	XP_011511226.1	20 - 21	3908		144
	XM_011512925.1	XP_011511227.1	19 - 20	3716		144
	XM_011512926.2	XP_011511228.1	20 - 21	3908		144
	XM_017006643.1	XP_016862132.1	19 - 20	3716		144
GenBank mRNA	U49844.1	-	20 - 21	3924		144
	U76308.1	-	20 - 21	3898		144
	Y09077.1	-	20 - 21	3898		144

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0300012670.hg.1
This assay targets the same location as HTA transcript cluster(s) TC03001854.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Homo sapiens, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene ATR

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase, protein modifying enzyme

Gene Ontology Categories:

Process(es)

DNA damage checkpoint
DNA replication
DNA repair
cellular response to DNA damage stimulus
cell cycle
multicellular organism development
negative regulation of DNA replication
peptidyl-serine phosphorylation
positive regulation of telomere maintenance via telomerase
cellular response to UV
interstrand cross-link repair
response to drug
positive regulation of DNA damage response, signal transduction by p53 class mediator
protein autophosphorylation
protein localization to chromosome, telomeric region
cellular response to gamma radiation
replicative senescence
establishment of RNA localization to telomere
establishment of macromolecular complex localization to telomere
regulation of cellular response to heat
regulation of signal transduction by p53 class mediator
positive regulation of telomerase catalytic core complex assembly

Function(s)

DNA binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
MutLalpha complex binding
MutSalpha complex binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR03033515.hg.1	TC03001854.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR03033515.hg.1	ENST00000350721.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03033515.hg.1	ENST00000383101.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR03033515.hg.1	NM_001184.3	Refseq
Affymetrix Human Clariom D Assay	PSR0300194712.hg.1	ENST00000350721.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0300194712.hg.1	NM_001184.3	Refseq
Affymetrix Human Clariom D Assay	PSR0300194712.hg.1	ENST00000350721.8	Ensembl
Affymetrix Human Clariom D Assay	PSR0300194712.hg.1	NM_001184.3	Refseq
Affymetrix Human Clariom D Assay	PSR0300194712.hg.1	TC0300012670.hg.1	Clariom D TC