Hs01000485_g1

• Gene Symbol: SOCS3
• Gene Name: suppressor of cytokine signaling 3
• Gene Aliases: ATOD4, CIS3, Cish3, SOCS-3, SSI-3, SSI3
• Chromosome Location: Chr.17: 78356777 - 78360079 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: SOCS3
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_003955.4	NP_003946.3	1 - 2	326		111
GenBank mRNA	AK309756.1	-	1 - 2	324		111
	AK314212.1	-	1 - 2	324		111
	AU134017.1	-	1 - 2	324		111
	BC060858.1	-	1 - 2	324	30333577	111
	BE245649.1	-	1 - 2	145		111
	DA671124.1	-	1 - 2	326		111

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC1700011903.hg.1
This assay targets the same location as HTA transcript cluster(s) TC17001917.hg.1

Additional Information:

This assay is in the 5'UTR region of the AK314212.1,BC060858.1,NM_003955.4 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Apoptosis, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, 1700, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene SOCS3

Panther Classification:

Molecular Function -

kinase modulator

Gene Ontology Categories:

Process(es)

response to hypoxia
negative regulation of protein kinase activity
JAK-STAT cascade
aging
response to heat
response to gamma radiation
protein ubiquitination
cytokine-mediated signaling pathway
organ regeneration
response to food
response to estradiol
response to lipopolysaccharide
response to progesterone
response to insulin
regulation of growth
response to drug
negative regulation of tyrosine phosphorylation of Stat1 protein
positive regulation of tyrosine phosphorylation of Stat3 protein
negative regulation of tyrosine phosphorylation of Stat3 protein
negative regulation of apoptotic process
positive regulation of cell differentiation
negative regulation of JAK-STAT cascade
negative regulation of insulin receptor signaling pathway
negative regulation of inflammatory response
response to glucocorticoid
regulation of interferon-gamma-mediated signaling pathway
branching involved in labyrinthine layer morphogenesis
placenta blood vessel development
trophoblast giant cell differentiation
spongiotrophoblast differentiation

Function(s)

protein kinase inhibitor activity
protein binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR17025973.hg.1	ENST00000330871.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR17025973.hg.1	NM_003955.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR17025973.hg.1	TC17001917.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR17025971.hg.1	ENST00000330871.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR17025971.hg.1	NM_003955.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR17025971.hg.1	TC17001917.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	ENST00000587578.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	ENST00000587578.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	ENST00000587578.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Transcriptome Array 2.0	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR17025972.hg.1	ENST00000330871.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR17025972.hg.1	NM_003955.4	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR17025972.hg.1	TC17001917.hg.1	HTA TC
Affymetrix Human Clariom D Assay	PSR1700197044.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	PSR1700197044.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	PSR1700197044.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	PSR1700197044.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	PSR1700197044.hg.1	TC1700011903.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	PSR1700197045.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	PSR1700197045.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	PSR1700197045.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	PSR1700197045.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	PSR1700197045.hg.1	TC1700011903.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	ENST00000587578.1	Ensembl
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	ENST00000587578.1	Ensembl
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	ENST00000587578.1	Ensembl
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	TC1700011903.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	PSR1700197042.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	PSR1700197042.hg.1	ENST00000587578.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1700197042.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	PSR1700197042.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	PSR1700197042.hg.1	ENST00000587578.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1700197042.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	PSR1700197042.hg.1	TC1700011903.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	PSR1700197043.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	PSR1700197043.hg.1	ENST00000587578.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1700197043.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	PSR1700197043.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	PSR1700197043.hg.1	ENST00000587578.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1700197043.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	PSR1700197043.hg.1	TC1700011903.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	PSR1700197046.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	PSR1700197046.hg.1	ENST00000587578.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1700197046.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	PSR1700197046.hg.1	ENST00000330871.3	Ensembl
Affymetrix Human Clariom D Assay	PSR1700197046.hg.1	ENST00000587578.1	Ensembl
Affymetrix Human Clariom D Assay	PSR1700197046.hg.1	NM_003955.4	Refseq
Affymetrix Human Clariom D Assay	PSR1700197046.hg.1	TC1700011903.hg.1	Clariom D TC

Array Name	Probe IDs	Targets	Target Type
ABI Human Genome Survey Microarray Version 2.0	156493	-	-