Hs01003408_m1

• Gene Symbol: DNMT3B
• Gene Name: DNA methyltransferase 3 beta
• Gene Aliases: ICF, ICF1, M.HsaIIIB
• Chromosome Location: Chr.20: 32762385 - 32809356 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: DNMT3B
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_006892.3	NP_008823.1	21 - 22	2628		75
	NM_175848.1	NP_787044.1	20 - 21	2568		75
	NM_175850.2	NP_787046.1	20 - 21	2547		75
GenBank mRNA	AF129267.1	-	4 - 5	402		75
	AF156488.1	-	21 - 22	2421		75
	AF176228.1	-	20 - 21	2547		75
	AF331857.1	-	21 - 22	2628		75
	DQ321787.1	-	20 - 21	2662		75

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC2000007132.hg.1
This assay targets the same location as HTA transcript cluster(s) TC20000215.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene DNMT3B

Panther Classification:

Molecular Function -

DNA methyltransferase

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
response to hypoxia
DNA methylation
response to toxic substance
response to ionizing radiation
DNA methylation on cytosine within a CG sequence
positive regulation of gene expression
response to activity
response to caffeine
response to estradiol
response to vitamin A
response to cocaine
response to drug
positive regulation of neuron differentiation
negative regulation of gene expression, epigenetic
S-adenosylhomocysteine metabolic process
S-adenosylmethioninamine metabolic process
positive regulation of histone H3-K4 methylation
negative regulation of histone H3-K9 methylation
cellular response to hyperoxia
cellular response to dexamethasone stimulus
C-5 methylation of cytosine

Function(s)

chromatin binding
transcription corepressor activity
DNA (cytosine-5-)-methyltransferase activity
protein binding
DNA-methyltransferase activity
histone deacetylase binding
unmethylated CpG binding
metal ion binding
DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR20002683.hg.1	ENST00000201963.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR20002683.hg.1	ENST00000328111.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR20002683.hg.1	ENST00000353855.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR20002683.hg.1	NM_006892.3	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20002683.hg.1	NM_175848.1	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20002683.hg.1	NM_175850.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR20002683.hg.1	TC20000215.hg.1	HTA TC
Affymetrix Human Clariom D Assay	PSR2000148782.hg.1	ENST00000201963.3	Ensembl
Affymetrix Human Clariom D Assay	PSR2000148782.hg.1	ENST00000328111.6	Ensembl
Affymetrix Human Clariom D Assay	PSR2000148782.hg.1	ENST00000353855.6	Ensembl
Affymetrix Human Clariom D Assay	PSR2000148782.hg.1	NM_006892.3	Refseq
Affymetrix Human Clariom D Assay	PSR2000148782.hg.1	NM_175848.1	Refseq
Affymetrix Human Clariom D Assay	PSR2000148782.hg.1	NM_175850.2	Refseq
Affymetrix Human Clariom D Assay	PSR2000148782.hg.1	TC2000007132.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	PSR2000148782.hg.1	ENST00000201963.3	Ensembl
Affymetrix Human Clariom D Assay	PSR2000148782.hg.1	ENST00000328111.6	Ensembl
Affymetrix Human Clariom D Assay	PSR2000148782.hg.1	ENST00000353855.6	Ensembl
Affymetrix Human Clariom D Assay	PSR2000148782.hg.1	NM_006892.3	Refseq
Affymetrix Human Clariom D Assay	PSR2000148782.hg.1	NM_175848.1	Refseq
Affymetrix Human Clariom D Assay	PSR2000148782.hg.1	NM_175850.2	Refseq