Hs01004356_m1

• Gene Symbol: C5
• Gene Name: complement component 5
• Gene Aliases: C5D, C5a, C5b, CPAMD4, ECLZB
• Chromosome Location: Chr.9: 120952335 - 121075174 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: C5
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001317163.1	NP_001304092.1	23 - 24	3300		82
	NM_001735.2	NP_001726.2	23 - 24	2974		82
	XM_011518980.2	XP_011517282.1	24 - 25	3343		82
	XM_017015102.1	XP_016870591.1	25 - 26	3495		82
	XM_017015103.1	XP_016870592.1	23 - 24	3128		82
	XM_017015104.1	XP_016870593.1	25 - 26	3495		82
GenBank mRNA	AB209031.1	-	23 - 24	3300		82
	BC113738.1	-	23 - 24	2969	8322790	82
	BC113740.1	-	23 - 24	2969	8322792	82
	M57729.1	-	23 - 24	2956		82
	M65134.1	-	13 - 14	1711		82

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0900011394.hg.1
This assay targets the same location as HTA transcript cluster(s) TC09001542.hg.1

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene C5

Panther Classification:

Molecular Function -

protease inhibitor

Gene Ontology Categories:

Process(es)

activation of MAPK activity
in utero embryonic development
chemotaxis
response to stress
inflammatory response
complement activation
complement activation, alternative pathway
complement activation, classical pathway
cell surface receptor signaling pathway
G-protein coupled receptor signaling pathway
positive regulation of vascular endothelial growth factor production
negative regulation of macrophage chemotaxis
negative regulation of endopeptidase activity
cytolysis
regulation of complement activation
positive regulation of angiogenesis
cell chemotaxis
positive regulation of chemokine secretion
mitophagy in response to mitochondrial depolarization

Function(s)

endopeptidase inhibitor activity
receptor binding
protein binding
chemokine activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR09019409.hg.1	TC09001542.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR09019409.hg.1	ENST00000223642.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR09019409.hg.1	ENST00000430906.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR09019409.hg.1	NM_001735.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR09019407.hg.1	TC09001542.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR09019407.hg.1	ENST00000223642.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR09019407.hg.1	ENST00000430906.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR09019407.hg.1	NM_001735.2	Refseq
Affymetrix Human Clariom D Assay	PSR0900177717.hg.1	ENST00000223642.2	Ensembl
Affymetrix Human Clariom D Assay	PSR0900177717.hg.1	NM_001735.2	Refseq
Affymetrix Human Clariom D Assay	PSR0900177717.hg.1	ENST00000223642.2	Ensembl
Affymetrix Human Clariom D Assay	PSR0900177717.hg.1	NM_001735.2	Refseq
Affymetrix Human Clariom D Assay	PSR0900177717.hg.1	TC0900011394.hg.1	Clariom D TC