Hs01007074_g1

• Gene Symbol: ERBB2
• Gene Name: erb-b2 receptor tyrosine kinase 2
• Gene Aliases: CD340, HER-2, HER-2/neu, HER2, MLN 19, NEU, NGL, TKR1
• Chromosome Location: Chr.17: 39688084 - 39728662 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: ERBB2
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001005862.2	NP_001005862.1	1 - 2	200		119
	NM_001289936.1	NP_001276865.1	1 - 2	200		119
	NM_001289938.1	NP_001276867.1	1 - 2	200		119
GenBank mRNA	AB025286.1	-	1 - 2	183		119
	AK295195.1	-	1 - 2	200		119
	BC110392.1	-	1 - 2	165		119
	BI755753.1	-	1 - 2	165		119

More Information

Updated Mapping Information

This assay targets the same location as HTA transcript cluster(s) TC17000480.hg.1

Additional Information:

This assay is in the 5'UTR region of the AK295195.1,NM_001005862.2,NM_001289936.1,NM_001289938.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Apoptosis, Protein Kinase, Mammalian Gene Collection, Detect Genomic DNA, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene ERBB2

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

MAPK cascade
positive regulation of protein phosphorylation
transcription, DNA-templated
protein phosphorylation
signal transduction
cell surface receptor signaling pathway
enzyme linked receptor protein signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
peripheral nervous system development
heart development
neuromuscular junction development
motor neuron axon guidance
cell proliferation
phosphatidylinositol 3-kinase signaling
regulation of phosphatidylinositol 3-kinase signaling
peptidyl-tyrosine phosphorylation
positive regulation of cell growth
regulation of microtubule-based process
negative regulation of immature T cell proliferation in thymus
ERBB2 signaling pathway
wound healing
myelination
positive regulation of MAP kinase activity
positive regulation of GTPase activity
positive regulation of translation
regulation of angiogenesis
positive regulation of cell adhesion
positive regulation of transcription from RNA polymerase I promoter
positive regulation of transcription from RNA polymerase III promoter
protein autophosphorylation
phosphatidylinositol phosphorylation
phosphatidylinositol-mediated signaling
oligodendrocyte differentiation
positive regulation of epithelial cell proliferation
regulation of ERK1 and ERK2 cascade
cellular response to growth factor stimulus
cellular response to epidermal growth factor stimulus
positive regulation of protein targeting to membrane
regulation of cell motility

Function(s)

RNA polymerase I core binding
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
receptor signaling protein tyrosine kinase activity
transmembrane signaling receptor activity
Ras guanyl-nucleotide exchange factor activity
protein binding
ATP binding
protein C-terminus binding
growth factor binding
protein phosphatase binding
identical protein binding
ErbB-3 class receptor binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
protein heterodimerization activity
protein dimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR17005664.hg.1	NM_001005862.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR17005664.hg.1	TC17000480.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR17005663.hg.1	ENST00000406381.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR17005663.hg.1	NM_001005862.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR17005663.hg.1	TC17000480.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR17005666.hg.1	ENST00000406381.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR17005666.hg.1	NM_001005862.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR17005666.hg.1	TC17000480.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR17005662.hg.1	ENST00000406381.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR17005662.hg.1	NM_001005862.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR17005662.hg.1	TC17000480.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000430460.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000430460.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000430460.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000430460.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000430460.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000430460.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000438143.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000438143.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000438143.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000438143.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000438143.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000438143.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000451851.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000451851.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000451851.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000451851.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000451851.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000451851.1	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0200015048.hg.1	ENST00000451851.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000428283.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000430460.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000430460.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000430460.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000430460.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000430460.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000430460.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000438143.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000438143.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000438143.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000438143.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000438143.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000438143.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000451851.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000451851.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000451851.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000451851.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000451851.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000451851.1	Ensembl
Affymetrix Human Clariom D Assay	TC0200015048.hg.1	ENST00000451851.1	Ensembl