Hs01008316_m1

• Gene Symbol: ITCH
• Gene Name: itchy E3 ubiquitin protein ligase
• Gene Aliases: ADMFD, AIF4, AIP4, NAPP1
• Chromosome Location: Chr.20: 34363235 - 34511773 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: ITCH
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_001324197.1	NP_001311126.1	1 - 2	117		152
	NM_001324198.1	NP_001311127.1	1 - 2	117		152

More Information

Additional Information:

This assay is in the 5'UTR region of the NM_001324197.1, NM_001324198.1 transcripts.

• Set Membership: Amplicon length greater than or equal to 101, Homo sapiens, Probe spans exons

Panther Classification:

Molecular Function -

ubiquitin-protein ligase

Gene Ontology Categories:

Process(es)

regulation of cell growth
positive regulation of T cell anergy
ubiquitin-dependent protein catabolic process
apoptotic process
inflammatory response
Notch signaling pathway
protein ubiquitination
negative regulation of NF-kappaB transcription factor activity
negative regulation of type I interferon production
protein K29-linked ubiquitination
protein ubiquitination involved in ubiquitin-dependent protein catabolic process
negative regulation of apoptotic process
innate immune response
positive regulation of protein catabolic process
negative regulation of JNK cascade
negative regulation of alpha-beta T cell proliferation
viral entry into host cell
negative regulation of defense response to virus
defense response to virus
nucleotide-binding oligomerization domain containing signaling pathway
protein K63-linked ubiquitination
protein K48-linked ubiquitination
regulation of protein deubiquitination

Function(s)

ubiquitin-protein transferase activity
protein binding
ligase activity
ubiquitin-like protein transferase activity
ribonucleoprotein complex binding
CXCR chemokine receptor binding
ubiquitin protein ligase activity