Hs01011515_m1

• Gene Symbol: IL12B
• Gene Name: interleukin 12B
• Gene Aliases: CLMF, CLMF2, IL-12B, IMD28, IMD29, NKSF, NKSF2
• Chromosome Location: Chr.5: 159314783 - 159330473 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: IL12B
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_002187.2	NP_002178.2	2 - 3	131		123
GenBank mRNA	AF180563.1	-	1 - 2	95		123
	BC067498.1	-	1 - 2	93	6971868	123
	BC067499.1	-	1 - 2	93	6971869	123
	BC067500.1	-	1 - 2	93	6971872	123
	BC067501.1	-	1 - 2	93	6971873	123
	BC067502.1	-	1 - 2	93	6971874	123
	BC074723.2	-	2 - 3	120	30915173	123
	EF173865.1	-	1 - 2	57		123
	M65272.1	-	2 - 3	131		123
	M65290.1	-	1 - 2	102		123

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0500012646.hg.1
This assay targets the same location as HTA transcript cluster(s) TC05001997.hg.1

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Mammalian Gene Collection, Homo sapiens, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene IL12B

Panther Classification:

Molecular Function -

transmembrane signal receptor

Gene Ontology Categories:

Process(es)

positive regulation of T cell mediated cytotoxicity
positive regulation of defense response to virus by host
natural killer cell activation involved in immune response
positive regulation of T-helper 1 type immune response
positive regulation of natural killer cell mediated cytotoxicity directed against tumor cell target
negative regulation of inflammatory response to antigenic stimulus
cell cycle arrest
response to UV-B
positive regulation of activation of JAK2 kinase activity
cell migration
cytokine-mediated signaling pathway
sensory perception of pain
sexual reproduction
natural killer cell activation
negative regulation of interleukin-10 production
negative regulation of interleukin-17 production
positive regulation of granulocyte macrophage colony-stimulating factor production
positive regulation of interferon-gamma production
positive regulation of interleukin-10 production
positive regulation of interleukin-12 production
positive regulation of interleukin-17 production
positive regulation of tumor necrosis factor production
positive regulation of natural killer cell activation
positive regulation of natural killer cell proliferation
positive regulation of mononuclear cell proliferation
positive regulation of tissue remodeling
positive regulation of smooth muscle cell apoptotic process
regulation of cytokine biosynthetic process
T-helper 1 type immune response
T-helper cell differentiation
interferon-gamma biosynthetic process
positive regulation of T cell proliferation
positive regulation of activated T cell proliferation
positive regulation of NF-kappaB import into nucleus
regulation of tyrosine phosphorylation of Stat1 protein
positive regulation of tyrosine phosphorylation of Stat3 protein
positive regulation of tyrosine phosphorylation of Stat4 protein
positive regulation of tyrosine phosphorylation of Stat5 protein
defense response to protozoan
positive regulation of memory T cell differentiation
negative regulation of growth of symbiont in host
positive regulation of interferon-gamma biosynthetic process
positive regulation of osteoclast differentiation
positive regulation of cell adhesion
negative regulation of smooth muscle cell proliferation
positive regulation of lymphocyte proliferation
positive regulation of inflammatory response
defense response to Gram-negative bacterium
positive regulation of NK T cell activation
positive regulation of NK T cell proliferation
defense response to virus
cellular response to lipopolysaccharide
cellular response to interferon-gamma
positive regulation of T-helper 17 type immune response
positive regulation of T-helper 17 cell lineage commitment

Function(s)

cytokine receptor activity
cytokine activity
interleukin-12 receptor binding
protein binding
growth factor activity
interleukin-12 alpha subunit binding
identical protein binding
protein homodimerization activity
interleukin-23 receptor binding
protein heterodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR05027816.hg.1	TC05001997.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR05027816.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05027816.hg.1	NM_002187.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	TC0500012646.hg.1	NM_002187.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0500012646.hg.1	NM_002187.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0500012646.hg.1	NM_002187.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0500012646.hg.1	NM_002187.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0500012646.hg.1	NM_002187.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0500012646.hg.1	NM_002187.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0500012646.hg.1	NM_002187.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0500012646.hg.1	NM_002187.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0500012646.hg.1	NM_002187.2	Refseq
Affymetrix Human Transcriptome Array 2.0	TC0500012646.hg.1	NM_002187.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR05027817.hg.1	TC05001997.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR05027817.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05027817.hg.1	NM_002187.2	Refseq
Affymetrix Human Transcriptome Array 2.0	PSR05027819.hg.1	TC05001997.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR05027819.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR05027819.hg.1	NM_002187.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500188219.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Clariom D Assay	PSR0500188219.hg.1	NM_002187.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500188219.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Clariom D Assay	PSR0500188219.hg.1	NM_002187.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500188219.hg.1	TC0500012646.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Clariom D Assay	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Clariom D Assay	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Clariom D Assay	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Clariom D Assay	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Clariom D Assay	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Clariom D Assay	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Clariom D Assay	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Clariom D Assay	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Clariom D Assay	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Clariom D Assay	TC0500012646.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Clariom D Assay	TC0500012646.hg.1	NM_002187.2	Refseq
Affymetrix Human Clariom D Assay	TC0500012646.hg.1	NM_002187.2	Refseq
Affymetrix Human Clariom D Assay	TC0500012646.hg.1	NM_002187.2	Refseq
Affymetrix Human Clariom D Assay	TC0500012646.hg.1	NM_002187.2	Refseq
Affymetrix Human Clariom D Assay	TC0500012646.hg.1	NM_002187.2	Refseq
Affymetrix Human Clariom D Assay	TC0500012646.hg.1	NM_002187.2	Refseq
Affymetrix Human Clariom D Assay	TC0500012646.hg.1	NM_002187.2	Refseq
Affymetrix Human Clariom D Assay	TC0500012646.hg.1	NM_002187.2	Refseq
Affymetrix Human Clariom D Assay	TC0500012646.hg.1	NM_002187.2	Refseq
Affymetrix Human Clariom D Assay	TC0500012646.hg.1	NM_002187.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500188220.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Clariom D Assay	PSR0500188220.hg.1	NM_002187.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500188220.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Clariom D Assay	PSR0500188220.hg.1	NM_002187.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500188220.hg.1	TC0500012646.hg.1	Clariom D TC
Affymetrix Human Clariom D Assay	PSR0500188222.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Clariom D Assay	PSR0500188222.hg.1	NM_002187.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500188222.hg.1	ENST00000231228.2	Ensembl
Affymetrix Human Clariom D Assay	PSR0500188222.hg.1	NM_002187.2	Refseq
Affymetrix Human Clariom D Assay	PSR0500188222.hg.1	TC0500012646.hg.1	Clariom D TC