Hs01034257_m1

• Gene Symbol: TP53
• Gene Name: tumor protein p53
• Gene Aliases: BCC7, LFS1, P53, TRP53
• Chromosome Location: Chr.17: 7668402 - 7687550 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: TP53
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_000546.5	NP_000537.3	9 - 10	1199		83
	NM_001126112.2	NP_001119584.1	9 - 10	1196		83
	NM_001126115.1	NP_001119587.1	5 - 6	879		83
	NM_001126118.1	NP_001119590.1	8 - 9	1316		83
	NM_001276697.1	NP_001263626.1	5 - 6	879		83
	NM_001276760.1	NP_001263689.1	9 - 10	1199		83
	NM_001276761.1	NP_001263690.1	9 - 10	1196		83
GenBank mRNA	AB082923.1	-	9 - 10	1060		83
	AF307851.1	-	9 - 10	1132		83
	AK223026.1	-	3 - 4	292		83
	AK225838.1	-	9 - 10	1137		83
	AK297462.1	-	10 - 11	1064		83
	AK297927.1	-	10 - 11	1109		83
	AK312568.1	-	9 - 10	1141		83
	AM076970.1	-	8 - 9	964		83
	AY429684.1	-	8 - 9	997		83
	BC003596.1	-	9 - 10	1117	3544714	83
	BT019622.1	-	8 - 9	997		83
	DQ186650.1	-	5 - 6	875		83
	DQ191317.1	-	9 - 10	1186		83
	DQ263704.1	-	8 - 9	997		83
	DQ286964.1	-	9 - 10	1131		83
	EF101867.1	-	8 - 9	964		83
	FJ207420.1	-	9 - 10	1132		83
	JN214348.1	-	8 - 9	1042		83
	JN601513.1	-	8 - 9	997		83
	JN601514.1	-	8 - 9	997		83
	JN601515.1	-	8 - 9	997		83
	JN601516.1	-	9 - 10	971		83
	JN900492.1	-	8 - 9	1305		83
	JQ026207.1	-	8 - 9	987		83
	JQ026208.1	-	8 - 9	992		83
	JQ026209.1	-	8 - 9	1002		83
	JQ026210.1	-	8 - 9	992		83
	JQ694049.1	-	8 - 9	1020		83
	JQ694050.1	-	8 - 9	1020		83
	JQ694051.1	-	8 - 9	1020		83
	M14694.1	-	9 - 10	1122		83
	M14695.1	-	9 - 10	1118		83
	X01405.1	-	6 - 7	698		83
	X02469.1	-	9 - 10	1132		83
	X60011.1	-	8 - 9	997		83
	X60012.1	-	8 - 9	997		83
	X60013.1	-	8 - 9	997		83
	X60014.1	-	8 - 9	997		83
	X60015.1	-	8 - 9	997		83
	X60016.1	-	8 - 9	997		83
	X60017.1	-	8 - 9	997		83
	X60018.1	-	8 - 9	997		83
	X60019.1	-	8 - 9	997		83
	X60020.1	-	8 - 9	997		83

More Information

• Set Membership: Ambion siRNA available, Amplicon length between 71 and 85, Apoptosis, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene TP53

Panther Classification:

Molecular Function -

P53-like transcription factor

Gene Ontology Categories:

Process(es)

negative regulation of transcription from RNA polymerase II promoter
DNA strand renaturation
base-excision repair
nucleotide-excision repair
regulation of transcription, DNA-templated
transcription from RNA polymerase II promoter
protein complex assembly
cellular response to DNA damage stimulus
DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
ER overload response
cell cycle arrest
Ras protein signal transduction
multicellular organism development
cell aging
protein localization
cell proliferation
negative regulation of cell proliferation
determination of adult lifespan
response to X-ray
response to gamma radiation
positive regulation of gene expression
viral process
protein sumoylation
cell differentiation
negative regulation of cell growth
DNA damage response, signal transduction by p53 class mediator
positive regulation of histone deacetylation
chromatin assembly
mitotic G1 DNA damage checkpoint
positive regulation of protein oligomerization
cellular response to UV
cellular response to drug
cellular response to glucose starvation
intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
regulation of apoptotic process
positive regulation of apoptotic process
negative regulation of apoptotic process
entrainment of circadian clock by photoperiod
proteasome-mediated ubiquitin-dependent protein catabolic process
positive regulation of neuron apoptotic process
negative regulation of transcription, DNA-templated
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
response to antibiotic
positive regulation of protein export from nucleus
regulation of mitochondrial membrane permeability
negative regulation of fibroblast proliferation
circadian behavior
positive regulation of peptidyl-tyrosine phosphorylation
negative regulation of helicase activity
protein tetramerization
negative regulation of telomerase activity
positive regulation of thymocyte apoptotic process
positive regulation of cell cycle arrest
cellular response to hypoxia
cellular response to ionizing radiation
intrinsic apoptotic signaling pathway by p53 class mediator
positive regulation of release of cytochrome c from mitochondria
replicative senescence
oxidative stress-induced premature senescence
intrinsic apoptotic signaling pathway
oligodendrocyte apoptotic process
positive regulation of execution phase of apoptosis
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
regulation of signal transduction by p53 class mediator
regulation of cell cycle G2/M phase transition
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
positive regulation of reactive oxygen species metabolic process
positive regulation of intrinsic apoptotic signaling pathway

Function(s)

RNA polymerase II transcription factor activity, sequence-specific DNA binding
core promoter sequence-specific DNA binding
RNA polymerase II transcription factor binding
transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding
protease binding
p53 binding
DNA binding
chromatin binding
damaged DNA binding
double-stranded DNA binding
transcription factor activity, sequence-specific DNA binding
copper ion binding
protein binding
ATP binding
transcription factor binding
zinc ion binding
enzyme binding
protein kinase binding
protein phosphatase binding
receptor tyrosine kinase binding
ubiquitin protein ligase binding
histone acetyltransferase binding
identical protein binding
sequence-specific DNA binding
protein self-association
transcription regulatory region DNA binding
protein heterodimerization activity
protein N-terminus binding
chaperone binding
protein phosphatase 2A binding