Hs01039878_m1

• Gene Symbol: MAP3K5
• Gene Name: mitogen-activated protein kinase kinase kinase 5
• Gene Aliases: ASK1, MAPKKK5, MEKK5
• Chromosome Location: Chr.6: 136557046 - 136793098 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: MAP3K5
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_005923.3	NP_005914.1	12 - 13	2187		112
	XM_011535839.2	XP_011534141.2	13 - 14	2511		112
	XM_017010870.1	XP_016866359.1	13 - 14	2510		112
	XM_017010871.1	XP_016866360.1	13 - 14	2510		112
	XM_017010872.1	XP_016866361.1	13 - 14	2509		112
	XM_017010873.1	XP_016866362.1	13 - 14	2508		112
	XM_017010876.1	XP_016866365.1	11 - 12	1518		112
	XM_017010877.1	XP_016866366.1	11 - 12	1755		112
GenBank mRNA	AB209093.1	-	12 - 13	2291		112
	AK293953.1	-	12 - 13	1447		112
	AK294507.1	-	3 - 4	303		112
	BC054503.2	-	12 - 13	2134	6143181	112
	BC088829.1	-	12 - 13	2188	6007002	112
	D84476.2	-	12 - 13	2093		112
	U67156.1	-	12 - 13	2186		112

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0600013280.hg.1
This assay targets the same location as HTA transcript cluster(s) TC06002146.hg.1

Additional Information:

This assay is in the 5'UTR region of the AK294507.1 transcripts.

• Set Membership: Ambion siRNA available, Amplicon length greater than or equal to 101, Apoptosis, Protein Kinase, Mammalian Gene Collection, Homo sapiens, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene MAP3K5

Panther Classification:

Molecular Function -

non-receptor serine/threonine protein kinase

Gene Ontology Categories:

Process(es)

MAPK cascade
activation of MAPKK activity
response to ischemia
protein phosphorylation
JNK cascade
activation of JUN kinase activity
intrinsic apoptotic signaling pathway in response to oxidative stress
viral process
response to endoplasmic reticulum stress
p38MAPK cascade
positive regulation of apoptotic process
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
positive regulation of JUN kinase activity
innate immune response
positive regulation of myoblast differentiation
positive regulation of JNK cascade
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
cellular response to hydrogen peroxide
apoptotic signaling pathway
programmed necrotic cell death
positive regulation of neuron death
cellular response to reactive nitrogen species

Function(s)

magnesium ion binding
protein kinase activity
protein serine/threonine kinase activity
MAP kinase kinase kinase activity
protein binding
ATP binding
protein kinase binding
protein phosphatase binding
protein homodimerization activity

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR06027071.hg.1	TC06002146.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR06027071.hg.1	ENST00000355845.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR06027071.hg.1	ENST00000359015.4	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR06027071.hg.1	ENST00000367768.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR06027071.hg.1	NM_005923.3	Refseq
Affymetrix Human Clariom D Assay	PSR0600191949.hg.1	ENST00000359015.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0600191949.hg.1	NM_005923.3	Refseq
Affymetrix Human Clariom D Assay	PSR0600191949.hg.1	ENST00000359015.4	Ensembl
Affymetrix Human Clariom D Assay	PSR0600191949.hg.1	NM_005923.3	Refseq
Affymetrix Human Clariom D Assay	PSR0600191949.hg.1	TC0600013280.hg.1	Clariom D TC