Hs01059111_m1

• Gene Symbol: ABCA1
• Gene Name: ATP binding cassette subfamily A member 1
• Gene Aliases: ABC-1, ABC1, CERP, HDLDT1, TGD
• Chromosome Location: Chr.9: 104781002 - 104928246 on Build GRCh38
• Species: Human
• Species Specific ID (Flybase ID): -

Assay Details

Gene Symbol: ABCA1
Interrogated Sequence		Translated Protein	Exon Boundary	Assay Location	IMAGE Clone ID	Amplicon Length
RefSeq	NM_005502.3	NP_005493.2	24 - 25	3932		67
	XM_011518341.2	XP_011516643.1	25 - 26	3916		67
GenBank mRNA	AB055982.1	-	23 - 24	3528		67
	AB445477.1	-	23 - 24	3528		67
	AF165281.1	-	22 - 23	3468		67
	AF285167.1	-	24 - 25	3818		67
	AJ012376.1	-	22 - 23	3468		67
	BC146856.1	-	24 - 25	3742	9056784	67

More Information

Updated Mapping Information

This assay targets the same location as Clariom D transcript cluster(s) TC0900011072.hg.1
This assay targets the same location as HTA transcript cluster(s) TC09001434.hg.1

• Set Membership: Ambion siRNA available, Amplicon length less than or equal to 70, Transporter, Mammalian Gene Collection, Homo sapiens, Inventoried, Probe spans exons

Matching Ambion siRNAs:

Click here to find siRNAs for Gene ABCA1

Panther Classification:

Molecular Function -

ATP-binding cassette (ABC) transporter, primary active transporter, transporter

Gene Ontology Categories:

Process(es)

peptide secretion
protein lipidation
phagocytosis, engulfment
lysosome organization
G-protein coupled receptor signaling pathway
response to nutrient
cholesterol metabolic process
negative regulation of macrophage derived foam cell differentiation
positive regulation of cholesterol efflux
negative regulation of cholesterol storage
endosomal transport
positive regulation of cAMP biosynthetic process
intracellular cholesterol transport
regulation of Cdc42 protein signal transduction
cholesterol efflux
phospholipid efflux
high-density lipoprotein particle assembly
response to laminar fluid shear stress
apolipoprotein A-I-mediated signaling pathway
lipoprotein metabolic process
response to drug
cholesterol homeostasis
reverse cholesterol transport
phospholipid translocation
interleukin-1 beta secretion
phospholipid homeostasis
response to low-density lipoprotein particle
platelet dense granule organization
cellular response to lipopolysaccharide
cellular response to retinoic acid
cellular response to cholesterol
anion transmembrane transport

Function(s)

receptor binding
protein binding
ATP binding
phospholipid binding
phospholipid transporter activity
anion transmembrane transporter activity
cholesterol binding
cholesterol transporter activity
syntaxin binding
small GTPase binding
apolipoprotein binding
apolipoprotein A-I binding
apolipoprotein A-I receptor activity
ATPase activity, coupled to transmembrane movement of substances
ATPase binding

MicroArray Probes:

Array Name	Probe IDs	Targets	Target Type
Affymetrix Human Transcriptome Array 2.0	PSR09017865.hg.1	TC09001434.hg.1	HTA TC
Affymetrix Human Transcriptome Array 2.0	PSR09017865.hg.1	ENST00000374736.3	Ensembl
Affymetrix Human Transcriptome Array 2.0	PSR09017865.hg.1	NM_005502.3	Refseq
Affymetrix Human Clariom D Assay	PSR0900175462.hg.1	ENST00000374736.7	Ensembl
Affymetrix Human Clariom D Assay	PSR0900175462.hg.1	NM_005502.3	Refseq
Affymetrix Human Clariom D Assay	PSR0900175462.hg.1	ENST00000374736.7	Ensembl
Affymetrix Human Clariom D Assay	PSR0900175462.hg.1	NM_005502.3	Refseq
Affymetrix Human Clariom D Assay	PSR0900175462.hg.1	TC0900011072.hg.1	Clariom D TC